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MARK DONOWITZ, M.D.
M.D.
Gastroenterology Physician
NPI: 1306893342Individual
Specialties, Licenses & Credentials
Gastroenterology PhysicianPrimary
Internal Medicine — Gastroenterology
Code: 207RG0100X
D02767(MD)
Research & Publications (20)
The attrition of young physician-scientists: problems and potential solutions.
PMID 17258744·Gastroenterology·2007
8-other
Short-term regulation of NHE3 by EGF and protein kinase C but not protein kinase A involves vesicle trafficking in epithelial cells and fibroblasts.
PMID 11193592·Ann N Y Acad Sci·2000
6-review
Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis.
PMID 18974311·Am J Physiol Gastrointest Liver Physiol·2009
7-preclinical
Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: potential contributors to IBD-associated diarrhea.
PMID 18942765·Inflamm Bowel Dis·2009
7-preclinical
Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice.
PMID 18758809·Pflugers Arch·2009
7-preclinical
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.
PMID 19221439·J Clin Invest·2009
7-preclinical
NHERF3 (PDZK1) contributes to basal and calcium inhibition of NHE3 activity in Caco-2BBe cells.
PMID 19535329·J Biol Chem·2009
8-other
Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.
PMID 19473983·J Biol Chem·2009
7-preclinical
Regulation of intestinal electroneutral sodium absorption and the brush border Na+/H+ exchanger by intracellular calcium.
PMID 19538312·Ann N Y Acad Sci·2009
6-review
Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3.
PMID 18614797·Mol Biol Cell·2008
7-preclinical
Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease.
PMID 18218832·J Pharmacol Exp Ther·2008
7-preclinical
Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.
PMID 18256311·Am J Physiol Renal Physiol·2008
7-preclinical
Latrunculin B facilitates Shiga toxin 1 transcellular transcytosis across T84 intestinal epithelial cells.
PMID 18342638·Biochim Biophys Acta·2008
8-other
Fractionation of subcellular membrane vesicles of epithelial and nonepithelial cells by OptiPrep density gradient ultracentrifugation.
PMID 18369940·Methods Mol Biol·2008
7-preclinical
The epithelial brush border Na+/H+ exchanger NHE3 associates with the actin cytoskeleton by binding to ezrin directly and via PDZ domain-containing Na+/H+ exchanger regulatory factor (NHERF) proteins.
PMID 18430067·Clin Exp Pharmacol Physiol·2008
6-review
Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism.
PMID 19088451·Cell Physiol Biochem·2008
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 600 N WOLFE ST
BALTIMORE, MD 21287 - Phone
- (410) 955-4166
Quick Facts
- NPI
- 1306893342
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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