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ERIN HUSTON, DO
DO
Geriatric Medicine (Internal Medicine) Physician
NPI: 1386076859IndividualAccepts Medicare
Specialties, Licenses & Credentials
Geriatric Medicine (Internal Medicine) PhysicianPrimary
Internal Medicine — Geriatric Medicine
Code: 207RG0300X
2017-00662(NC)
Family Medicine Physician
Family Medicine
Code: 207Q00000X
2017-00662(NC)
Education
OTHER
Class of 2013
Research & Publications (18)
EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation.
PMID 18728186·Proc Natl Acad Sci U S A·2008
8-other
Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+.
PMID 16940352·J Cell Sci·2006
7-preclinical
cAMP phosphodiesterase-4A1 (PDE4A1) has provided the paradigm for the intracellular targeting of phosphodiesterases, a process that underpins compartmentalized cAMP signalling.
PMID 16856845·Biochem Soc Trans·2006
7-preclinical
The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3. Consequences for altered intracellular distribution.
PMID 10829034·J Biol Chem·2000
7-preclinical
MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization.
PMID 19153083·J Biol Chem·2009
8-other
PDE4 associates with different scaffolding proteins: modulating interactions as treatment for certain diseases.
PMID 18491051·Handb Exp Pharmacol·2008
6-review
Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes.
PMID 16356165·Biochem J·2006
8-other
DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling.
PMID 16293762·Science·2005
7-preclinical
In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
PMID 15905070·Cell Signal·2005
7-preclinical
Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene.
PMID 15738310·Mol Pharmacol·2005
4-observational
Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases.
PMID 15178638·Circ Res·2004
7-preclinical
Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene.
PMID 15025561·Biochem J·2004
7-preclinical
The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins.
PMID 14500724·J Biol Chem·2003
8-other
Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process.
PMID 12873709·Cell Signal·2003
7-preclinical
Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2.
PMID 12810716·J Biol Chem·2003
7-preclinical
TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid.
PMID 11994273·J Biol Chem·2002
7-preclinical
In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting.
PMID 11882390·Cell Signal·2002
7-preclinical
Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic amp-specific phosphodiesterase PDE4A10.
PMID 11306681·Mol Pharmacol·2001
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 4 locations total
- Address
- 2001 VAIL AVE, STE 400
CHARLOTTE, NC 28207 - Phone
- (704) 304-7000
Quick Facts
- NPI
- 1386076859
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 2
- Locations
- 4
- Years in Practice
- 13
- Publications
- 18
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