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DR. LAURENCE B PEARL M.D.
M.D.
Surgery Physician
NPI: 1386618841IndividualAccepts Medicare
Specialties, Licenses & Credentials
Surgery PhysicianPrimary
Surgery
Code: 208600000X
A69783(CA)
Education
BAYLOR COLLEGE OF MEDICINE
Class of 1994
Research & Publications (20)
The Hsp90 molecular chaperone: an open and shut case for treatment.
PMID 18290764·Biochem J·2008
6-review
Structure and mechanism of the Hsp90 molecular chaperone machinery.
PMID 16756493·Annu Rev Biochem·2006
6-review
Regulation of protein kinases in insulin, growth factor and Wnt signalling.
PMID 12504681·Curr Opin Struct Biol·2002
6-review
Structure, function, and mechanism of the Hsp90 molecular chaperone.
PMID 11868271·Adv Protein Chem·2001
6-review
Structure and function in the uracil-DNA glycosylase superfamily.
PMID 10946227·Mutat Res·2000
4-observational
Structural basis of the radicicol resistance displayed by a fungal hsp90.
PMID 19236053·ACS Chem Biol·2009
8-other
Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex--implications for clamp loading and regulation.
PMID 19446481·Mol Cell·2009
8-other
Structural-thermodynamic relationships of interactions in the N-terminal ATP-binding domain of Hsp90.
PMID 19631219·J Mol Biol·2009
8-other
Structural insights into formation of an active signaling complex between Rac and phospholipase C gamma 2.
PMID 19394299·Mol Cell·2009
8-other
A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s.
PMID 19032597·FEBS J·2009
8-other
Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK.
PMID 19155274·Nucleic Acids Res·2009
8-other
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer.
PMID 18020435·J Med Chem·2008
7-preclinical
Molecular characterization of macbecin as an Hsp90 inhibitor.
PMID 18357975·J Med Chem·2008
7-preclinical
The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis.
PMID 18256191·Development·2008
7-preclinical
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.
PMID 18413753·Cancer Res·2008
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 2 locations total
- Address
- 8907 Warner Ave Ste 201
Huntington Beach, CA 92647 - Phone
- (714) 842-8282
Quick Facts
- NPI
- 1386618841
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 2
- Years in Practice
- 32
- Publications
- 20
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