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DAVID LEAMAN, MD
MD
Cardiovascular Disease Physician
NPI: 1386692051Individual
Specialties, Licenses & Credentials
Cardiovascular Disease PhysicianPrimary
Internal Medicine — Cardiovascular Disease
Code: 207RC0000X
MD029317L(PA)
Research & Publications (20)
2-5A antisense treatment of respiratory syncytial virus.
PMID 16081320·Curr Opin Pharmacol·2005
6-review
Novel growth and death related interferon-stimulated genes (ISGs) in melanoma: greater potency of IFN-beta compared with IFN-alpha2.
PMID 14769151·J Interferon Cytokine Res·2003
4-observational
Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis.
PMID 12029096·J Biol Chem·2002
8-other
Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7.
PMID 19152337·Eur J Immunol·2009
7-preclinical
Genome-wide polysome profiling reveals an inflammation-responsive posttranscriptional operon in gamma interferon-activated monocytes.
PMID 19001086·Mol Cell Biol·2009
8-other
Identification of interferon-beta-stimulated genes that inhibit angiogenesis in vitro.
PMID 18937547·J Interferon Cytokine Res·2008
7-preclinical
Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.
PMID 18838548·J Exp Med·2008
4-observational
Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.
PMID 18499210·Virology·2008
7-preclinical
Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neurons.
PMID 18455990·Cell·2008
7-preclinical
Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a.
PMID 18330707·Apoptosis·2008
8-other
Pathomechanism of loss of elasticity and hypertrophy of lumbar ligamentum flavum in elderly patients with lumbar spinal canal stenosis.
PMID 18246001·Spine (Phila Pa 1976)·2007
4-observational
Lumbar ligamentum flavum hypertrophy is due to accumulation of inflammation-related scar tissue.
PMID 17495768·Spine (Phila Pa 1976)·2007
8-other
IFN-alpha1,8 inhibits tumor-induced angiogenesis in murine angiosarcomas.
PMID 16689662·J Interferon Cytokine Res·2006
7-preclinical
Human telomerase RNA degradation by 2'-5'-linked oligoadenylate antisense chimeras in a cell-free system, cultured tumor cells, and murine xenograft models.
PMID 16978086·Oligonucleotides·2006
7-preclinical
Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.
PMID 16801630·J Clin Oncol·2006
7-preclinical
Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse.
PMID 16728431·Int Immunol·2006
7-preclinical
Expression of RASSF1A, an epigenetically silenced tumor suppressor, overcomes resistance to apoptosis induction by interferons.
PMID 16510600·Cancer Res·2006
8-other
Pathomechanism of ligamentum flavum hypertrophy: a multidisciplinary investigation based on clinical, biomechanical, histologic, and biologic assessments.
PMID 16319751·Spine (Phila Pa 1976)·2005
4-observational
Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development.
PMID 15989958·Cell·2005
7-preclinical
Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection.
PMID 15705586·J Biol Chem·2005
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 2 locations total
- Address
- 500 UNIVERSITY DR
HERSHEY, PA 17033 - Phone
- (717) 531-8407
Quick Facts
- NPI
- 1386692051
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 2
- Publications
- 20
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