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BROOKE ROEBUCK, MD
MD
Pediatrics Physician
NPI: 1386905073Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
29288(OK)
Research & Publications (18)
Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.
PMID 19168568·Toxicol Sci·2009
7-preclinical
Chemical genomics of cancer chemopreventive dithiolethiones.
PMID 19126641·Carcinogenesis·2009
7-preclinical
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
PMID 18701497·Cancer Res·2008
7-preclinical
Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3.
PMID 18416522·Chem Res Toxicol·2008
7-preclinical
Quantification of urinary aflatoxin B1 dialdehyde metabolites formed by aflatoxin aldehyde reductase using isotope dilution tandem mass spectrometry.
PMID 18266327·Chem Res Toxicol·2008
7-preclinical
Grain size measurement by EBSD in complex hot deformed metal alloy microstructures.
PMID 17760627·J Microsc·2007
8-other
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.
PMID 17290047·Carcinogenesis·2007
7-preclinical
Lysosomes and trivalent arsenic treatment in acute promyelocytic leukemia.
PMID 17202112·J Natl Cancer Inst·2007
8-other
Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
PMID 16489057·Cancer Res·2006
7-preclinical
Post-initiation chlorophyllin exposure does not modulate aflatoxin-induced foci in the liver and colon of rats.
PMID 16460570·J Carcinog·2006
8-other
3H-1,2-dithiole-3-thione targets nuclear factor kappaB to block expression of inducible nitric-oxide synthase, prevents hypotension, and improves survival in endotoxemic rats.
PMID 16371450·J Pharmacol Exp Ther·2006
7-preclinical
Hyperplasia, partial hepatectomy, and the carcinogenicity of aflatoxin B1.
PMID 14743384·J Cell Biochem·2004
6-review
Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz.
PMID 14555609·Carcinogenesis·2003
7-preclinical
Identification of aflatoxin M1-N7-guanine in liver and urine of tree shrews and rats following administration of aflatoxin B1.
PMID 12971806·Chem Res Toxicol·2003
4-observational
Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol.
PMID 11872631·Carcinogenesis·2002
7-preclinical
Chemopreventive effect of oltipraz on AFB(1)-induced hepatocarcinogenesis in tree shrew model.
PMID 11819668·World J Gastroenterol·2000
8-other
Chemoprotection by organosulfur inducers of phase 2 enzymes: dithiolethiones and dithiins.
PMID 11201301·Drug Metabol Drug Interact·2000
6-review
Reduction of aflatoxin B(1) adduct biomarkers by oltipraz in the tree shrew (Tupaia belangeri chinensis).
PMID 10799742·Cancer Lett·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1272 W MAIN RD
MIDDLETOWN, RI 02842 - Phone
- (401) 847-2290
Quick Facts
- NPI
- 1386905073
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 18
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