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ROBERT SCHIRMER, M.D.
M.D.
Internal Medicine Physician
NPI: 1396898524Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
4301033853(MI)
Research & Publications (20)
Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial.
PMID 19415120·PLoS One·2009
3-trial
CA/C1 peptidases of the malaria parasites Plasmodium falciparum and P. berghei and their mammalian hosts--a bioinformatical analysis.
PMID 19663681·Biol Chem·2009
7-preclinical
Myristoylated adenylate kinase-2 of Plasmodium falciparum forms a heterodimer with myristoyltransferase.
PMID 18973776·Mol Biochem Parasitol·2009
7-preclinical
Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso.
PMID 18286187·PLoS One·2008
3-trial
Depletion of Plasmodium berghei plasmoredoxin reveals a non-essential role for life cycle progression of the malaria parasite.
PMID 18575607·PLoS One·2008
7-preclinical
Cytotoxic interactions of methylene blue with trypanosomatid-specific disulfide reductases and their dithiol products.
PMID 18448175·Mol Biochem Parasitol·2008
7-preclinical
Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum.
PMID 17967916·Antimicrob Agents Chemother·2008
7-preclinical
Molecular basis of glutathione reductase deficiency in human blood cells.
PMID 17185460·Blood·2007
5-case
Methylene blue for malaria in Africa: results from a dose-finding study in combination with chloroquine.
PMID 17026773·Malar J·2006
3-trial
A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme.
PMID 16910673·J Am Chem Soc·2006
7-preclinical
Eosin B as a novel antimalarial agent for drug-resistant Plasmodium falciparum.
PMID 16940112·Antimicrob Agents Chemother·2006
7-preclinical
Diagnosis of red cell G6PD deficiency in rural Burkina Faso: comparison of a rapid fluorescent enzyme test on filter paper with polymerase chain reaction based genotyping.
PMID 16225660·Br J Haematol·2005
4-observational
In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins.
PMID 16251300·Antimicrob Agents Chemother·2005
7-preclinical
Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster.
PMID 15644209·J Mol Biol·2005
4-observational
Dithiol proteins as guardians of the intracellular redox milieu in parasites: old and new drug targets in trypanosomes and malaria-causing plasmodia.
PMID 15657967·Angew Chem Int Ed Engl·2005
6-review
The conserved histidine 106 of large thioredoxin reductases is likely to have a structural role but not a base catalyst function.
PMID 15670839·FEBS Lett·2005
7-preclinical
1H, 13C, and 15N sequence-specific resonance assignment and secondary structure of Plasmodium falciparum thioredoxin.
PMID 16211497·J Biomol NMR·2005
7-preclinical
Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study.
PMID 16259789·Redox Rep·2005
2-rct
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1033 HEALTHCARE DR
CHARLOTTE, MI 48813 - Phone
- (517) 541-2673
Quick Facts
- NPI
- 1396898524
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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