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DOUGLAS JACOBUS, DDS, MD
DDS, MD
Oral and Maxillofacial Surgery (Dentist)
NPI: 1427443282Individual
Specialties, Licenses & Credentials
Oral and Maxillofacial Surgery (Dentist)Primary
Dentist — Oral and Maxillofacial Surgery
Code: 1223S0112X
22DI02641300(NJ)
Research & Publications (17)
Triclosan derivatives: towards potent inhibitors of drug-sensitive and drug-resistant Mycobacterium tuberculosis.
PMID 19130456·ChemMedChem·2009
8-other
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.
PMID 19064257·Cell Host Microbe·2008
7-preclinical
Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.
PMID 18320016·PLoS Negl Trop Dis·2008
7-preclinical
Multicenter randomized, double-blind, placebo-controlled, clinical trial of dapsone as a glucocorticoid-sparing agent in maintenance-phase pemphigus vulgaris.
PMID 18209165·Arch Dermatol·2008
4-observational
Role of specific cytochrome P450 isoforms in the conversion of phenoxypropoxybiguanide analogs in human liver microsomes to potent antimalarial dihydrotriazines.
PMID 18006651·Drug Metab Dispos·2008
8-other
Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate--JPC2056--in cynomolgus monkeys using an in vivo in vitro model.
PMID 17646199·J Antimicrob Chemother·2007
7-preclinical
X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy.
PMID 17567585·J Biol Chem·2007
7-preclinical
Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2'-substituted triclosan derivatives.
PMID 16466916·Bioorg Med Chem Lett·2006
4-observational
Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives.
PMID 16198563·Bioorg Med Chem Lett·2005
7-preclinical
Identification of the optimal third generation antifolate against P. falciparum and P. vivax.
PMID 16181688·Mol Biochem Parasitol·2005
7-preclinical
Triazine Inhibits Toxoplasma gondii tachyzoites in vitro and in vivo.
PMID 16048961·Antimicrob Agents Chemother·2005
7-preclinical
In vitro metabolism of phenoxypropoxybiguanide analogues in human liver microsomes to potent antimalarial dihydrotriazines.
PMID 15828818·J Med Chem·2005
7-preclinical
Effects of Lantana camara (Verbenaceae) on general reproductive performance and teratology in rats.
PMID 15733567·Toxicon·2005
4-observational
Effects of Lantana camara (Verbenaceae) on rat fertility.
PMID 12583691·Vet Hum Toxicol·2003
7-preclinical
Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase.
PMID 12384337·Antimicrob Agents Chemother·2002
8-other
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
PMID 11689078·J Med Chem·2001
7-preclinical
Population pharmacokinetics of dapsone in children with human immunodeficiency virus infection.
PMID 11452241·Clin Pharmacol Ther·2001
3-trial
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 2 locations total
- Address
- 110 BERGEN ST
NEWARK, NJ 07103 - Phone
- (973) 972-3126
Quick Facts
- NPI
- 1427443282
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 2
- Publications
- 17
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