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AMY GEDDIS, M.D.
M.D.
Pediatric Hematology & Oncology Physician
NPI: 1437220290Individual
Specialties, Licenses & Credentials
Pediatric Hematology & Oncology PhysicianPrimary
Pediatrics — Pediatric Hematology-Oncology
Code: 2080P0207X
MD00034728(WA)
Research & Publications (20)
Phosphatidylinositol 3-kinase is necessary but not sufficient for thrombopoietin-induced proliferation in engineered Mpl-bearing cell lines as well as in primary megakaryocytic progenitors.
PMID 11418622·J Biol Chem·2001
7-preclinical
Deletion of JAM-C, a candidate gene for heart defects in Jacobsen syndrome, results in a normal cardiac phenotype in mice.
PMID 19533782·Am J Med Genet A·2009
5-case
Congenital amegakaryocytic thrombocytopenia and thrombocytopenia with absent radii.
PMID 19327586·Hematol Oncol Clin North Am·2009
6-review
Compound heterozygous c-Mpl mutations in a child with congenital amegakaryocytic thrombocytopenia: functional characterization and a review of the literature.
PMID 19302922·Exp Hematol·2009
5-case
Inhibition of GSK-3beta promotes survival and proliferation of megakaryocytic cells through a beta-catenin-independent pathway.
PMID 18804163·Cell Signal·2008
8-other
PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1).
PMID 18256550·Cell Cycle·2008
7-preclinical
Diagnosis of immune thrombocytopenic purpura in children.
PMID 17934362·Curr Opin Hematol·2007
6-review
Endomitotic megakaryocytes that form a bipolar spindle exhibit cleavage furrow ingression followed by furrow regression.
PMID 17312391·Cell Cycle·2007
7-preclinical
Inherited thrombocytopenia: Congenital amegakaryocytic thrombocytopenia and thrombocytopenia with absent radii.
PMID 16822462·Semin Hematol·2006
6-review
Endomitotic megakaryocytes form a midzone in anaphase but have a deficiency in cleavage furrow formation.
PMID 16552179·Cell Cycle·2006
7-preclinical
The Mpl receptor expressed on endothelial cells does not contribute significantly to the regulation of circulating thrombopoietin levels.
PMID 16413394·Exp Hematol·2006
7-preclinical
Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCzeta or mTOR in TPO-dependent cell lines and primary megakaryocytes.
PMID 16380230·Cell Signal·2006
7-preclinical
The molecular basis of congenital thrombocytopenias: insights into megakaryopoiesis.
PMID 16188691·Hematology·2005
6-review
Temozolomide and radiation for aggressive pediatric central nervous system malignancies.
PMID 15891559·J Pediatr Hematol Oncol·2005
5-case
Connexin 26 (GJB2) gene-related deafness and speech intelligibility after cochlear implantation.
PMID 15547423·Otol Neurotol·2004
8-other
Auditory perception and speech discrimination after cochlear implantation in patients with connexin 26 (GJB2) gene-related deafness.
PMID 15547422·Otol Neurotol·2004
8-other
Megakaryocytes express functional Aurora-B kinase in endomitosis.
PMID 15130946·Blood·2004
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 4800 SAND POINT WAY NE, CENTER FOR BLOOD AND CANCER DISORDERS
SEATTLE, WA 98105 - Phone
- (206) 987-2106
Quick Facts
- NPI
- 1437220290
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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