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ORSOLYA POLGAR, MD
MD
Internal Medicine Physician
NPI: 1437383304IndividualAccepts Medicare
Education
OTHER
Class of 1994
Research & Publications (17)
Arginine 383 is a crucial residue in ABCG2 biogenesis.
PMID 19406100·Biochim Biophys Acta·2009
7-preclinical
The 315-316 deletion determines the BXP-21 antibody epitope but has no effect on the function of wild type ABCG2 or the Q141K variant.
PMID 19002564·Mol Cell Biochem·2009
8-other
ABCG2: structure, function and role in drug response.
PMID 18370855·Expert Opin Drug Metab Toxicol·2008
6-review
ABC transporters in the balance: is there a role in multidrug resistance?
PMID 15667317·Biochem Soc Trans·2005
6-review
Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells.
PMID 19132374·Cancer Chemother Pharmacol·2009
8-other
Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells.
PMID 18234970·Mol Cancer Res·2008
8-other
Reduced expression of DNA topoisomerase I in SF295 human glioblastoma cells selected for resistance to homocamptothecin and diflomotecan.
PMID 17984197·Mol Pharmacol·2008
4-observational
ABCG2: determining its relevance in clinical drug resistance.
PMID 17323127·Cancer Metastasis Rev·2007
6-review
Towards understanding the mechanism of action of the multidrug resistance-linked half-ABC transporter ABCG2: a molecular modeling study.
PMID 17027309·J Mol Graph Model·2007
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 3 locations total
- Address
- 8401 CONNECTICUT AVE PH SUITE
CHEVY CHASE, MD 20815 - Phone
- (888) 663-6331
Quick Facts
- NPI
- 1437383304
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 3
- Years in Practice
- 32
- Publications
- 17
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