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SERBAN CONSTANTINESCU, MD PHD
MD PHD
Nephrology Physician
NPI: 1487641262IndividualAccepts Medicare
Specialties, Licenses & Credentials
Nephrology PhysicianPrimary
Internal Medicine — Nephrology
Code: 207RN0300X
MD419687(PA)
CMS Specialties
PrimaryNEPHROLOGY
Education
OTHER
Class of 1986
Research & Publications (20)
Ligand-independent thrombopoietin mutant receptor requires cell surface localization for endogenous activity.
PMID 19261614·J Biol Chem·2009
7-preclinical
Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers.
PMID 19139102·J Biol Chem·2009
7-preclinical
Structural changes of piezoelectric La3Ga5SiO14 induced by paramagnetic ions revealed by 71Ga multiple quantum magic angle spinning.
PMID 19596562·Solid State Nucl Magn Reson·2009
8-other
A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis.
PMID 19164538·Proc Natl Acad Sci U S A·2009
7-preclinical
A new era for small molecule screening: from new targets, such as JAK2 V617F, to complex cellular screens.
PMID 19183237·J Cell Mol Med·2009
8-other
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
PMID 19620628·J Exp Med·2009
7-preclinical
SOCS3 tyrosine phosphorylation as a potential bio-marker for myeloproliferative neoplasms associated with mutant JAK2 kinases.
PMID 19229050·Haematologica·2009
7-preclinical
JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies.
PMID 18682296·Semin Cell Dev Biol·2008
6-review
Ligand-independent homomeric and heteromeric complexes between interleukin-2 or -9 receptor subunits and the gamma chain.
PMID 18829468·J Biol Chem·2008
8-other
Substitution of pseudokinase domain residue Val-617 by large non-polar amino acids causes activation of JAK2.
PMID 18326042·J Biol Chem·2008
7-preclinical
The JAK2V617F mutation can occur in a hematopoietic stem cell that exhibits no proliferative advantage: a case of human allogeneic transplantation.
PMID 18650474·Blood·2008
5-case
Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif.
PMID 18474601·J Biol Chem·2008
8-other
The Stat3-activating Tyk2 V678F mutant does not up-regulate signaling through the type I interferon receptor but confers ligand hypersensitivity to a homodimeric receptor.
PMID 18456658·J Biol Chem·2008
8-other
Aberrant signal transduction pathways in myeloproliferative neoplasms.
PMID 18769448·Leukemia·2008
6-review
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.
PMID 18362173·J Exp Med·2008
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 3401 N BROAD ST
PHILADELPHIA, PA 19140 - Phone
- (215) 707-4600
Quick Facts
- NPI
- 1487641262
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 40
- Publications
- 20
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