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JAMES BRADNER, MD
MD
Hematology & Oncology Physician
NPI: 1518920867Individual
Specialties, Licenses & Credentials
Hematology & Oncology PhysicianPrimary
Internal Medicine — Hematology & Oncology
Code: 207RH0003X
216495(MA)
Research & Publications (20)
Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis.
PMID 19386607·J Biol Chem·2009
8-other
A method for the covalent capture and screening of diverse small molecules in a microarray format.
PMID 17406478·Nat Protoc·2006
8-other
A robust small-molecule microarray platform for screening cell lysates.
PMID 16720270·Chem Biol·2006
8-other
The application of PCR for the isolation of a lipase gene from the genomic DNA of an Antarctic microfungus.
PMID 13680154·Curr Genet·2003
4-observational
Metabolic activity in filamentous fungi can be analysed by flow cytometry.
PMID 12782375·J Microbiol Methods·2003
8-other
Identification of glutathione S-transferase pi as a protein involved in Parkinson disease progression.
PMID 19498008·Am J Pathol·2009
7-preclinical
HDAC2 negatively regulates memory formation and synaptic plasticity.
PMID 19424149·Nature·2009
7-preclinical
A role for a novel protein, nucleolin, in Parkinson's disease.
PMID 19409963·Neurosci Lett·2009
8-other
Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning.
PMID 19395640·Development·2009
7-preclinical
Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.
PMID 19317450·J Med Chem·2009
7-preclinical
Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold.
PMID 19239241·Org Lett·2009
8-other
Rab11a and HSP90 regulate recycling of extracellular alpha-synuclein.
PMID 19193894·J Neurosci·2009
4-observational
Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole.
PMID 19193120·J Am Chem Soc·2009
8-other
Fungi from koala (Phascolarctos cinereus) faeces exhibit a broad range of enzyme activities against recalcitrant substrates.
PMID 19141036·Lett Appl Microbiol·2009
7-preclinical
Ubiquitin proteasome system stress underlies synergistic killing of ovarian cancer cells by bortezomib and a novel HDAC6 inhibitor.
PMID 19010849·Clin Cancer Res·2008
8-other
Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor.
PMID 18642817·J Am Chem Soc·2008
8-other
HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells.
PMID 18591380·Blood·2008
8-other
Structural origin of selectivity in class II-selective histone deacetylase inhibitors.
PMID 18412327·J Med Chem·2008
8-other
PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib.
PMID 18089823·Cancer Res·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 44 BINNEY ST, DANA-FARBER CANCER INSTITUTE
BOSTON, MA 02115 - Phone
- (617) 632-6629
Quick Facts
- NPI
- 1518920867
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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