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EUGENE KERNS, MD

MD

Obstetrics & Gynecology Physician

NPI: 1518931153Individual

Specialties, Licenses & Credentials

Obstetrics & Gynecology PhysicianPrimary

Obstetrics & Gynecology

Code: 207V00000X

19961(IA)

Research & Publications (20)

Discovery of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride (GAP-134)13, an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation.
PMID 19175320·J Med Chem·2009
7-preclinical
Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands.
PMID 19433358·Bioorg Med Chem Lett·2009
8-other
Comparison of blood-brain barrier permeability assays: in situ brain perfusion, MDR1-MDCKII and PAMPA-BBB.
PMID 18837012·J Pharm Sci·2009
4-observational
Drug-like property concepts in pharmaceutical design.
PMID 19601822·Curr Pharm Des·2009
6-review
Identification of a series of benzoxazoles as potent 5-HT6 ligands.
PMID 19152787·Bioorg Med Chem Lett·2009
8-other
1-Sulfonylindazoles as potent and selective 5-HT6 ligands.
PMID 19345582·Bioorg Med Chem Lett·2009
7-preclinical
Current drug metabolism.
PMID 18991579·Curr Drug Metab·2008
7-preclinical
In vitro solubility assays in drug discovery.
PMID 18991584·Curr Drug Metab·2008
6-review
Solution stability--plasma, gastrointestinal, bioassay.
PMID 18991582·Curr Drug Metab·2008
6-review
Applications of high throughput microsomal stability assay in drug discovery.
PMID 18673274·Comb Chem High Throughput Screen·2008
7-preclinical
A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands.
PMID 18583130·Bioorg Med Chem Lett·2008
8-other
Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes.
PMID 17390370·Chirality·2007
6-review
Development of a liquid chromatography/tandem mass spectrometry method for the quantitation of acetylcholine and related neurotransmitters in brain microdialysis samples.
PMID 17383138·J Pharm Biomed Anal·2007
7-preclinical
Ultra-performance liquid chromatography/tandem mass spectrometric quantification of structurally diverse drug mixtures using an ESI-APCI multimode ionization source.
PMID 17295426·Rapid Commun Mass Spectrom·2007
8-other
Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC-MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC-MS.
PMID 17137735·Int J Pharm·2007
4-observational
Development and application of an automated solution stability assay for drug discovery.
PMID 16234336·J Biomol Screen·2006
8-other
Utility of mass spectrometry for pharmaceutical profiling applications.
PMID 16787155·Curr Drug Metab·2006
6-review
Biological assay challenges from compound solubility: strategies for bioassay optimization.
PMID 16635808·Drug Discov Today·2006
6-review
High throughput microsomal stability assay for insoluble compounds.
PMID 16621364·Int J Pharm·2006
4-observational
Integrity profiling of high throughput screening hits using LC-MS and related techniques.
PMID 16178805·Comb Chem High Throughput Screen·2005
6-review

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
2322 E KIMBERLY RD
DAVENPORT, IA 52807

Location

Practice Location

2322 E KIMBERLY RD, DAVENPORT, IA
(563) 355-1853

Quick Facts

NPI
1518931153
Entity Type
Individual
Gender
Male
Medicare
Not confirmed
Specialties
1
Locations
1
Publications
20

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