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JENNIFER VACCA, MD

MD

Internal Medicine Physician

NPI: 1528251873Individual

Specialties, Licenses & Credentials

Internal Medicine PhysicianPrimary

Internal Medicine

Code: 207R00000X

48229(CO)4301511266(MI)

Research & Publications (20)

Discovery of aminoheterocycles as a novel beta-secretase inhibitor class: pH dependence on binding activity part 1.
PMID 19409780·Bioorg Med Chem Lett·2009
8-other
The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists.
PMID 19577468·Bioorg Med Chem Lett·2009
7-preclinical
Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants.
PMID 19631528·Bioorg Med Chem Lett·2009
8-other
The discovery of highly potent CGRP receptor antagonists.
PMID 19010673·Bioorg Med Chem Lett·2009
7-preclinical
Evolution of tertiary carbinamine BACE-1 inhibitors: Abeta reduction in rhesus CSF upon oral dosing.
PMID 19085994·ChemMedChem·2009
7-preclinical
First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primates.
PMID 18854490·J Pharmacol Exp Ther·2009
7-preclinical
Synthesis of the (3R,6S)-3-amino-6-(2,3-difluorophenyl)azepan-2-one of telcagepant (MK-0974), a calcitonin gene-related peptide receptor antagonist for the treatment of migraine headache.
PMID 18590336·Org Lett·2008
8-other
Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase.
PMID 18774711·Bioorg Med Chem Lett·2008
7-preclinical
Potent benzimidazolone-based CGRP receptor antagonists.
PMID 18947992·Bioorg Med Chem Lett·2008
7-preclinical
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase.
PMID 18811140·J Med Chem·2008
8-other

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

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Address
401 HALL ST SW STE 263
GRAND RAPIDS, MI 49503

Quick Facts

NPI
1528251873
Entity Type
Individual
Gender
Female
Medicare
Not confirmed
Specialties
2
Locations
1
Publications
20

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