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LAURA LAZARUS, MD
MD
Surgical Oncology Physician
NPI: 1598792590IndividualAccepts Medicare
Specialties, Licenses & Credentials
Surgery Physician
Surgery
Code: 208600000X
MD60956390(WA)
Surgical Oncology PhysicianPrimary
Surgery — Surgical Oncology
Code: 2086X0206X
MD60956390(WA)
Education
OTHER
Class of 1996
Research & Publications (20)
Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold.
PMID 19062273·Bioorg Med Chem Lett·2009
8-other
Influence of the side chain next to C-terminal benzimidazole in opioid pseudopeptides containing the Dmt-Tic pharmacophore.
PMID 19642675·J Med Chem·2009
7-preclinical
Orally administered H-Dmt-Tic-Lys-NH-CH2-Ph (MZ-2), a potent mu/delta-opioid receptor antagonist, regulates obese-related factors in mice.
PMID 19576206·Eur J Pharmacol·2009
7-preclinical
Na+ mechanism of delta-opioid receptor induced protection from anoxic K+ leakage in the cortex.
PMID 19189047·Cell Mol Life Sci·2009
7-preclinical
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic.
PMID 18680274·J Med Chem·2008
7-preclinical
Inhibition of the development of morphine tolerance by a potent dual mu-delta-opioid antagonist, H-Dmt-Tic-Lys-NH-CH2-Ph.
PMID 18571706·Pharmacol Biochem Behav·2008
7-preclinical
Role of benzimidazole (Bid) in the delta-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH(2)-Bid (UFP-502).
PMID 18178091·Bioorg Med Chem·2008
7-preclinical
Synthesis of a potent and selective (18)F-labeled delta-opioid receptor antagonist derived from the Dmt-Tic pharmacophore for positron emission tomography imaging.
PMID 18311909·J Med Chem·2008
7-preclinical
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist.
PMID 18069089·Peptides·2008
7-preclinical
Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides.
PMID 18468445·Bioorg Med Chem·2008
7-preclinical
Design and synthesis of opioidmimetics containing 2',6'-dimethyl-L-tyrosine and a pyrazinone-ring platform.
PMID 17826995·Bioorg Med Chem Lett·2007
8-other
A new opioid designed multiple ligand derived from the micro opioid agonist endomorphin-2 and the delta opioid antagonist pharmacophore Dmt-Tic.
PMID 17851080·Bioorg Med Chem·2007
8-other
Replacing the general energy-coupling proteins of the phospho-enol-pyruvate: sugar phosphotransferase system of Salmonella typhimurium with fructose-inducible counterparts results in the inability to utilize nonphosphotransferase system sugars.
PMID 17668017·Can J Microbiol·2007
8-other
Transformation of mu-opioid receptor agonists into biologically potent mu-opioid receptor antagonists.
PMID 17142049·Bioorg Med Chem·2007
7-preclinical
A phase I/II trial of 125I methylene blue for one-stage sentinel lymph node biopsy.
PMID 17245184·Ann Surg·2007
3-trial
Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore.
PMID 17339114·Bioorg Med Chem·2007
7-preclinical
Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligands.
PMID 17497839·J Med Chem·2007
7-preclinical
[N-allyl-Dmt1]-endomorphins are micro-opioid receptor antagonists lacking inverse agonist properties.
PMID 17626793·J Pharmacol Exp Ther·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1221 MADISON ST STE 600
SEATTLE, WA 98104 - Phone
- (206) 215-5900
Quick Facts
- NPI
- 1598792590
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 2
- Locations
- 1
- Years in Practice
- 30
- Publications
- 20
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