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JOHN LAZO, MD
MD
Emergency Medicine Physician
NPI: 1669512562Individual
Specialties, Licenses & Credentials
Emergency Medicine PhysicianPrimary
Emergency Medicine
Code: 207P00000X
35.046691(OH)
Research & Publications (20)
The substrate recognition domains of the N-end rule pathway.
PMID 19008229·J Biol Chem·2009
7-preclinical
Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages.
PMID 19578332·Nat Chem Biol·2009
7-preclinical
Cdc25B dual-specificity phosphatase inhibitors identified in a high-throughput screen of the NIH compound library.
PMID 19530895·Assay Drug Dev Technol·2009
8-other
Discovery of novel Myc-Max heterodimer disruptors with a three-dimensional pharmacophore model.
PMID 19215087·J Med Chem·2009
7-preclinical
Comparative study of the removal of phenolic compounds by biological and non-biological adsorbents.
PMID 18990486·J Hazard Mater·2009
4-observational
Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice.
PMID 18509642·Cancer Chemother Pharmacol·2009
7-preclinical
Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases.
PMID 19028102·Bioorg Med Chem·2009
8-other
Nitrosative stress suppresses checkpoint activation after DNA synthesis inhibition.
PMID 19158509·Cell Cycle·2009
8-other
Automated image-based phenotypic analysis in zebrafish embryos.
PMID 19235725·Dev Dyn·2009
7-preclinical
Microtubule binding and disruption and induction of premature senescence by disorazole C(1).
PMID 19066338·J Pharmacol Exp Ther·2009
7-preclinical
Development, validation and implementation of immobilized metal affinity for phosphochemicals (IMAP)-based high-throughput screening assays for low-molecular-weight compound libraries.
PMID 18714303·Nat Protoc·2008
4-observational
Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone.
PMID 18829454·J Biol Chem·2008
8-other
Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B.
PMID 18802630·Org Biomol Chem·2008
8-other
A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells.
PMID 18245669·Mol Cancer Ther·2008
8-other
Toward a molecular understanding of the interaction of dual specificity phosphatases with substrates: insights from structure-based modeling and high throughput screening.
PMID 18855677·Curr Med Chem·2008
6-review
Development of a 384-well colorimetric assay to quantify hydrogen peroxide generated by the redox cycling of compounds in the presence of reducing agents.
PMID 18699726·Assay Drug Dev Technol·2008
8-other
Is a step backwards in S-phase-targeted chemotherapy a step forward?
PMID 18693192·Mol Interv·2008
7-preclinical
Rear-view mirrors and crystal balls: a brief reflection on drug discovery.
PMID 18403648·Mol Interv·2008
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 7007 POWERS BLVD
PARMA, OH 44129 - Phone
- (330) 493-4443
Quick Facts
- NPI
- 1669512562
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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