Back to Search
JOEL SOMMERS, MD
MD
Emergency Medicine Physician
NPI: 1679541775Individual
Specialties, Licenses & Credentials
Emergency Medicine PhysicianPrimary
Emergency Medicine
Code: 207P00000X
MD424843(PA)
Research & Publications (20)
FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.
PMID 19419957·J Biol Chem·2009
8-other
FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange.
PMID 19150983·J Biol Chem·2009
8-other
Processing of DNA replication and repair intermediates by the concerted action of RecQ helicases and Rad2 structure-specific nucleases.
PMID 18221018·Protein Pept Lett·2008
6-review
Fair game: an approach to the job fair for family medicine residents.
PMID 18556502·Can Fam Physician·2008
8-other
Roles of norepinephrine, free Fatty acids, thyroid status, and skeletal muscle uncoupling protein 3 expression in sympathomimetic-induced thermogenesis.
PMID 17012607·J Pharmacol Exp Ther·2007
7-preclinical
Applying the RE-AIM framework to assess the public health impact of policy change.
PMID 17927550·Ann Behav Med·2007
8-other
FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein.
PMID 17596542·Blood·2007
8-other
An intervention to promote healthy weight: Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) theory and design.
PMID 17572971·Prev Chronic Dis·2007
8-other
Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand.
PMID 17145708·Nucleic Acids Res·2006
8-other
p53 modulates RPA-dependent and RPA-independent WRN helicase activity.
PMID 15735006·Cancer Res·2005
8-other
The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA.
PMID 16326861·Nucleic Acids Res·2005
8-other
Molecular epidemiology of microbial contamination in the operating room environment: Is there a risk for infection?
PMID 16269284·Surgery·2005
8-other
Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases.
PMID 15965237·J Biol Chem·2005
8-other
Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1.
PMID 15899892·J Biol Chem·2005
8-other
Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer.
PMID 15878853·J Biol Chem·2005
8-other
In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication.
PMID 15282207·Hum Mol Genet·2004
8-other
Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein.
PMID 15187093·J Biol Chem·2004
7-preclinical
Stimulation of flap endonuclease-1 by the Bloom's syndrome protein.
PMID 14688284·J Biol Chem·2004
8-other
WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork.
PMID 14657243·Mol Biol Cell·2004
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 100 E LEHIGH AVENUE
PHILADELPHIA, PA 19125 - Phone
- (215) 707-1656
Quick Facts
- NPI
- 1679541775
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
Are you this provider?
Claim Your Profile