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NICOLE KIEFFER, D.O.

D.O.

Rheumatology Physician

NPI: 1689854853IndividualAccepts Medicare

Specialties, Licenses & Credentials

Internal Medicine Physician

Internal Medicine

Code: 207R00000X

OP60447300(WA)
Rheumatology PhysicianPrimary

Internal Medicine — Rheumatology

Code: 207RR0500X

OP60447300(WA)53103(WI)

CMS Specialties

PrimaryRHEUMATOLOGY

Education

MIDWESTERN UNIVERSITY, CHICAGO COLLEGE OF OSTEOPATHIC MED

Class of 2006

Research & Publications (20)

Overexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells.
PMID 19486276·J Thromb Haemost·2009
7-preclinical
The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation.
PMID 19329429·J Biol Chem·2009
5-case
Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta.
PMID 19141530·FASEB J·2009
8-other
Testicular cancer in Luxembourg: incidence and outcome in relation to the different histo-pathological types (1980-2004).
PMID 19024372·Bull Soc Sci Med Grand Duche Luxemb·2008
8-other
The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis.
PMID 18648521·PLoS One·2008
7-preclinical
The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.
PMID 18577523·J Biol Chem·2008
7-preclinical
RGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase.
PMID 18398066·Blood·2008
8-other
A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia.
PMID 18065693·Blood·2008
5-case
The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.
PMID 17430904·J Biol Chem·2007
7-preclinical
Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis.
PMID 17163422·Int J Cancer·2007
8-other

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

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Contact & Hours

Address
2223 LIME KILN RD STE 1
GREEN BAY, WI 54311

Quick Facts

NPI
1689854853
Entity Type
Individual
Gender
Female
Medicare
Accepted
Specialties
3
Locations
1
Years in Practice
20
Publications
20

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