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DONALD PILCH, MD
MD
Psychiatry Physician
NPI: 1689992539Individual
Specialties, Licenses & Credentials
Psychiatry PhysicianPrimary
Psychiatry & Neurology — Psychiatry
Code: 2084P0800X
268365(NY)
Research & Publications (20)
Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations.
PMID 19309154·J Med Chem·2009
7-preclinical
Targeting human telomeric G-quadruplex DNA with oxazole-containing macrocyclic compounds.
PMID 18439430·Biochimie·2008
8-other
Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency.
PMID 18515097·Bioorg Med Chem Lett·2008
7-preclinical
Lysinyl macrocyclic hexaoxazoles: synthesis and selective G-quadruplex stabilizing properties.
PMID 18248989·Bioorg Med Chem Lett·2008
8-other
Topoisomerase I-mediated DNA cleavage induced by the minor groove-directed binding of bibenzimidazoles to a distal site.
PMID 17095016·J Mol Biol·2007
8-other
Collaborative roles of gammaH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair.
PMID 17123873·DNA Repair (Amst)·2007
7-preclinical
Use of 2-aminopurine as a fluorescent tool for characterizing antibiotic recognition of the bacterial rRNA A-site.
PMID 18431442·Tetrahedron·2007
8-other
Defining the molecular forces that determine the impact of neomycin on bacterial protein synthesis: importance of the 2'-amino functionality.
PMID 17353247·Antimicrob Agents Chemother·2007
8-other
Molecular determinants of antibiotic recognition and resistance by aminoglycoside phosphotransferase (3')-IIIa: a calorimetric and mutational analysis.
PMID 17418235·J Mol Biol·2007
8-other
Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA.
PMID 17452355·Nucleic Acids Res·2007
8-other
Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites.
PMID 17705310·Chembiochem·2007
8-other
Drug self-association modulates the cellular bioavailability of DNA minor groove-directed terbenzimidazoles.
PMID 16913713·J Med Chem·2006
8-other
Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage.
PMID 16219777·Genetics·2006
4-observational
Complete thermodynamic characterization of the multiple protonation equilibria of the aminoglycoside antibiotic paromomycin: a calorimetric and natural abundance 15N NMR study.
PMID 16326918·Biophys J·2006
8-other
Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity.
PMID 16433544·J Am Chem Soc·2006
8-other
Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles.
PMID 16735121·Bioorg Med Chem Lett·2006
8-other
Defining the basis for the specificity of aminoglycoside-rRNA recognition: a comparative study of drug binding to the A sites of Escherichia coli and human rRNA.
PMID 15663932·J Mol Biol·2005
4-observational
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1106 E GENESEE ST
SYRACUSE, NY 13210 - Phone
- (315) 466-1525
Quick Facts
- NPI
- 1689992539
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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