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DR. BLAKE ALLISTER LE GRAND MD
MD
Pediatrics Physician
NPI: 1699272567Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
25MA11081300(NJ)308910(NY)
Research & Publications (20)
PAR1 antagonist mediated antithrombotic activity in extracorporeal arterio-venous shunt in the rat.
PMID 19476974·Thromb Res·2010
7-preclinical
3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine bromhydrate (F 15845) prevents ischemia-induced heart remodeling by reduction of the intracellular Na+ overload.
PMID 19515969·J Pharmacol Exp Ther·2009
7-preclinical
Effects of a new PAR1 antagonist, F 16618, on smooth muscle cell contraction.
PMID 19344702·Eur J Pharmacol·2009
7-preclinical
F 15845 inhibits persistent sodium current in the heart and prevents angina in animal models.
PMID 19133985·Br J Pharmacol·2009
7-preclinical
Is postconditioning effective in prevention against long-lasting myocardial ischemia in the rabbit?
PMID 19093726·Physiol Res·2009
7-preclinical
Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes.
PMID 18326052·Mol Pharmacol·2008
4-observational
Letter by Pignier and Le Grand regarding article "Acute administration of fish oil inhibits triggered activity in isolated myocytes from rabbits and patients with heart failure".
PMID 18625900·Circulation·2008
7-preclinical
Sodium late current blockers in ischemia reperfusion: is the bullet magic?
PMID 18529044·J Med Chem·2008
7-preclinical
Downregulation of the calcium current in human right atrial myocytes from patients in sinus rhythm but with a high risk of atrial fibrillation.
PMID 18397872·Eur Heart J·2008
8-other
Direct protective effects of poly-unsaturated fatty acids, DHA and EPA, against activation of cardiac late sodium current: a mechanism for ischemia selectivity.
PMID 17891522·Basic Res Cardiol·2007
7-preclinical
Pharmacological characterization of protease activated receptor-1 by a serum responsive element-dependent reporter gene assay: major role of calmodulin.
PMID 16524561·Biochem Pharmacol·2006
7-preclinical
Pharmacological characterisation of sodium channels in sinoatrial node pacemaking in the rat heart.
PMID 16368090·Eur J Pharmacol·2006
7-preclinical
A novel steroid-like compound F90927 exerting positive-inotropic effects in cardiac muscle.
PMID 16474419·Br J Pharmacol·2006
7-preclinical
Cardioprotection of cariporide evaluated by plasma myoglobin and troponin I in myocardial infarction in pigs.
PMID 16573710·Fundam Clin Pharmacol·2006
7-preclinical
Drug evaluation: dronedarone, a novel non-iodinated anti-arrhythmic agent.
PMID 17002263·Curr Opin Investig Drugs·2006
6-review
Donitriptan decreases jugular venous oxygen saturation in rats in the absence of cranial vasoconstriction: an overlooked mechanism of antimigraine action?
PMID 16027226·J Pharmacol Exp Ther·2005
7-preclinical
KC 12291: an atypical sodium channel blocker with myocardial antiischemic properties.
PMID 14978516·Cardiovasc Drug Rev·2004
6-review
Study of the interaction of lubeluzole with cardiac sodium channels.
PMID 14576504·J Cardiovasc Pharmacol·2003
7-preclinical
Donitriptan selectively decreases jugular venous oxygen saturation in the anesthetized pig: further insights into its mechanism of action relevant to headache relief.
PMID 12606602·J Pharmacol Exp Ther·2003
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 7 locations total
- Address
- 325 S HIGHLAND AVE STE 106
BRIARCLIFF MANOR, NY 10510 - Phone
- (914) 366-0015
Locations (7)
Practice Location
325 S HIGHLAND AVE STE 106, BRIARCLIFF MANOR, NY
(914) 366-0015
Practice Location
5740 Broadway, Bronx, NY
(929) 920-5437
Practice Location
1983 Route 52, Hopewell Junction, NY
(845) 897-4500
Practice Location
620 E BOSTON POST RD, MAMARONECK, NY
(914) 777-5437
PM PEDIATRICS OF BAYSIDE PLLC
19 SPRING VALLEY MARKET PLACE, SPRING VALLEY, NY
(845) 371-5437
Practice Location
100 WOODS RD, VALHALLA, NY
(914) 493-6668
Practice Location
2290 CENTRAL PARK AVE, YONKERS, NY
(914) 337-5437
Quick Facts
- NPI
- 1699272567
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 7
- Publications
- 20
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