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BERNADETTE CLEMENT, MD
MD
Pediatrics Physician
NPI: 1699720805Individual
Specialties, Licenses & Credentials
Research & Publications (20)
Diacetyldiamidoximeester of pentamidine, a prodrug for treatment of protozoal diseases: synthesis, in vitro and in vivo biotransformation.
PMID 17001612·ChemMedChem·2006
7-preclinical
Reduction of Nomega-hydroxy-L-arginine to L-arginine by pig liver microsomes, mitochondria, and human liver microsomes.
PMID 16959215·Biochem Biophys Res Commun·2006
7-preclinical
Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid).
PMID 16118330·Drug Metab Dispos·2005
4-observational
Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes.
PMID 15862605·Life Sci·2005
7-preclinical
A two-step synthesis of cytostatically active benzo[c]phenanthridine derivatives.
PMID 15593276·Angew Chem Int Ed Engl·2005
8-other
Characterization of in vitro biotransformation of new, orally active, direct thrombin inhibitor ximelagatran, an amidoxime and ester prodrug.
PMID 12695354·Drug Metab Dispos·2003
7-preclinical
Reduction of N-hydroxylated compounds: amidoximes (N-hydroxyamidines) as pro-drugs of amidines.
PMID 12214667·Drug Metab Rev·2002
6-review
Phase 2 metabolites of N-hydroxylated amidines (amidoximes): synthesis, in vitro formation by pig hepatocytes, and mutagenicity testing.
PMID 11258982·Chem Res Toxicol·2001
7-preclinical
Reduction of amphetamine hydroxylamine and other aliphatic hydroxylamines by benzamidoxime reductase and human liver microsomes.
PMID 11080052·Chem Res Toxicol·2000
7-preclinical
A refined characterisation of the NeoHepatocyte phenotype necessitates a reappraisal of the transdifferentiation hypothesis.
PMID 19272525·Differentiation·2009
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
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Contact & Hours
- Address
- 650 FULTON ST
BROOKLYN, NY 11217 - Phone
- (718) 596-9800
Quick Facts
- NPI
- 1699720805
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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