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RICHARD HIRSCHMANN, M.D.
M.D.
Anesthesiology Physician
NPI: 1760428924Individual
Specialties, Licenses & Credentials
Anesthesiology PhysicianPrimary
Anesthesiology
Code: 207L00000X
Research & Publications (20)
Development of an efficient, regio- and stereoselective route to libraries based on the beta-D-glucose scaffold.
PMID 11101390·J Org Chem·2000
8-other
Catechol: A minimal scaffold for non-peptide peptidomimetics of the i + 1 and i + 2 positions of the beta-turn of somatostatin.
PMID 16986909·Org Lett·2006
8-other
A single amino acid mutation contributes to adaptive beach mouse color pattern.
PMID 16825572·Science·2006
7-preclinical
Design and synthesis of potent cystine-free cyclic hexapeptide agonists at the human urotensin receptor.
PMID 16623554·Org Lett·2006
8-other
Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains.
PMID 16298527·Bioorg Med Chem Lett·2006
7-preclinical
Replacement of Phe6, Phe7, and Phe11 of D-Trp8-somatostatin-14 with L-pyrazinylalanine. Predicted and observed effects on binding affinities at hSST2 and hSST4. An unexpected effect of the chirality of Trp8 on NMR spectra in methanol.
PMID 15943475·J Med Chem·2005
8-other
Synthesis and binding affinities of novel SRIF-mimicking beta-D-glucosides satisfying the requirement for a pi-cloud at C1.
PMID 15760154·Org Lett·2005
8-other
A practical synthesis of Nalpha-Fmoc-L-pyrazinylalanine via Schöllkopf's chiral auxiliary.
PMID 15686544·J Pept Res·2005
8-other
Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics.
PMID 15673249·Org Lett·2005
8-other
Novel chimeric scaffolds to extend the exploration of receptor space: hybrid beta-D-glucose-benzoheterodiazepine structures for broad screening. Effect of amide alkylation on the course of cyclization reactions.
PMID 14725439·J Org Chem·2004
8-other
Effects of heterocyclic aromatic substituents on binding affinities at two distinct sites of somatostatin receptors. Correlation with the electrostatic potential of the substituents.
PMID 12723949·J Med Chem·2003
8-other
Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors.
PMID 12723947·J Med Chem·2003
7-preclinical
Investigation of an antibody-ligase. Evidence for strain-induced catalysis.
PMID 12657273·Bioorg Med Chem Lett·2003
8-other
First generation design, synthesis, and evaluation of azepine-based cryptophycin analogues.
PMID 11735585·Org Lett·2001
7-preclinical
Design and synthesis of novel scaffolds for drug discovery: hybrids of beta-D-glucose with 1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-one, the corresponding 1-oxazepine, and 2- and 4-pyridyldiazepines.
PMID 11277802·Org Lett·2001
8-other
Intramolecular hydrogen-bond participation in phosphonylammonium salt formation.
PMID 11101445·Org Lett·2000
8-other
Design, synthesis, and evaluation of a pyrrolinone-based matrix metalloprotease inhibitor.
PMID 11101425·Org Lett·2000
8-other
Synthesis of a substance P antagonist with a somatostatin scaffold: factors affecting agonism/antagonism at GPCRs and the role of pseudosymmetry.
PMID 11052787·J Med Chem·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 2650 RIDGE AVE, EVANSTON HOSPITAL
EVANSTON, IL 60201 - Phone
- (847) 570-1206
Quick Facts
- NPI
- 1760428924
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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