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MARTHA FRALEY, MD

MD

Pediatrics Physician

NPI: 1780701649Individual

Specialties, Licenses & Credentials

Pediatrics PhysicianPrimary

Pediatrics

Code: 208000000X

33073(CO)208000000X(CO)

Research & Publications (20)

Positive allosteric modulators of the metabotropic glutamate receptor 2 for the treatment of schizophrenia.
PMID 19552508·Expert Opin Ther Pat·2009
6-review
3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6.
PMID 16978863·Bioorg Med Chem Lett·2006
8-other
Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP.
PMID 16439123·Bioorg Med Chem Lett·2006
8-other
Property-based design of KDR kinase inhibitors.
PMID 15032725·Curr Med Chem·2004
6-review
Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors: effects of 5-amido- and 5-sulphonamido-indolyl groups on pharmacokinetics and hERG binding.
PMID 14698157·Bioorg Med Chem Lett·2004
7-preclinical
Discovery and evaluation of 3-(5-thien-3-ylpyridin-3-yl)-1H-indoles as a novel class of KDR kinase inhibitors.
PMID 12941314·Bioorg Med Chem Lett·2003
7-preclinical
Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics.
PMID 12443771·Bioorg Med Chem Lett·2002
7-preclinical
Synthesis and initial SAR studies of 3,6-disubstituted pyrazolo[1,5-a]pyrimidines: a new class of KDR kinase inhibitors.
PMID 12217372·Bioorg Med Chem Lett·2002
8-other
Development of thioquinazolinones, allosteric Chk1 kinase inhibitors.
PMID 19155174·Bioorg Med Chem Lett·2009
8-other
Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer.
PMID 18578472·J Med Chem·2008
8-other

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

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Contact & Hours

Address
810 EAST 3RD ST, SUITE #301, PEDIATRIC PARTNERS OF THE SOUTHWEST
DURANGO, CO 81301

Quick Facts

NPI
1780701649
Entity Type
Individual
Gender
Female
Medicare
Not confirmed
Specialties
2
Locations
1
Publications
20

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