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MICHAEL TORTORELLA, MD
MD
Obstetrics & Gynecology Physician
NPI: 1801810965IndividualAccepts Medicare
Specialties, Licenses & Credentials
Specialist
Specialist
Code: 174400000X
ME45967(FL)
Obstetrics & Gynecology PhysicianPrimary
Obstetrics & Gynecology
Code: 207V00000X
ME45967(FL)
CMS Specialties
PrimaryOBSTETRICS/GYNECOLOGY
Education
UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE
Class of 1981
Research & Publications (20)
Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4).
PMID 12392761·Matrix Biol·2002
4-observational
The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage.
PMID 10827174·J Biol Chem·2000
7-preclinical
Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4).
PMID 10751421·J Biol Chem·2000
8-other
A review of the ADAMTS family, pharmaceutical targets of the future.
PMID 19601837·Curr Pharm Des·2009
6-review
Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors.
PMID 19586907·J Biol Chem·2009
4-observational
Kidney transplantation at Annunziata Hospital of Cosenza: report of 10 years experience.
PMID 19460507·Transplant Proc·2009
8-other
Intra-articular injection of tumor necrosis factor-alpha in the rat: an acute and reversible in vivo model of cartilage proteoglycan degradation.
PMID 19026578·Osteoarthritis Cartilage·2009
7-preclinical
Proprotein convertase activation of aggrecanases in cartilage in situ.
PMID 18671934·Arch Biochem Biophys·2008
8-other
Will the real aggrecanase(s) step up: evaluating the criteria that define aggrecanase activity in osteoarthritis.
PMID 18289053·Curr Pharm Biotechnol·2008
6-review
High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2).
PMID 17991750·J Biol Chem·2008
8-other
Identification and characterization of UK-201844, a novel inhibitor that interferes with human immunodeficiency virus type 1 gp160 processing.
PMID 17646410·Antimicrob Agents Chemother·2007
8-other
Substrate-dependent inhibition kinetics of an active site-directed inhibitor of ADAMTS-4 (Aggrecanase 1).
PMID 17487981·Biochemistry·2007
7-preclinical
A high performance liquid chromatography assay for monitoring proprotein convertase activity.
PMID 17391681·J Chromatogr A·2007
8-other
Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate.
PMID 17311924·J Biol Chem·2007
8-other
Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5.
PMID 17265492·Arthritis Rheum·2007
8-other
Identification of fibronectin neoepitopes present in human osteoarthritic cartilage.
PMID 16948117·Arthritis Rheum·2006
8-other
ADAMTS-4 (aggrecanase-1): N-terminal activation mechanisms.
PMID 16289022·Arch Biochem Biophys·2005
7-preclinical
Exaled nitric oxide and air trapping correlation in asthmatic children.
PMID 16197478·Allergy·2005
8-other
Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network.
PMID 14744861·J Biol Chem·2004
7-preclinical
Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes.
PMID 14715656·J Biol Chem·2004
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 7300 SANDLAKE COMMONS BLVD, SUITE 320
ORLANDO, FL 32819 - Phone
- (407) 363-1003
Quick Facts
- NPI
- 1801810965
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 2
- Locations
- 1
- Years in Practice
- 45
- Publications
- 20
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