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EVAN SWAYZE, MD

MD

Emergency Medicine Physician

NPI: 1821143694IndividualAccepts Medicare

Specialties, Licenses & Credentials

Emergency Medicine PhysicianPrimary

Emergency Medicine

Code: 207P00000X

237762(MA)

CMS Specialties

PrimaryEMERGENCY MEDICINE

Education

UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY

Class of 2000

Research & Publications (20)

Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals.
PMID 17182632·Nucleic Acids Res·2007
7-preclinical
SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets.
PMID 12190303·J Med Chem·2002
8-other
Effect of dose and plasma concentration on liver uptake and pharmacologic activity of a 2'-methoxyethyl modified chimeric antisense oligonucleotide targeting PTEN.
PMID 19393225·Biochem Pharmacol·2009
7-preclinical
Short antisense oligonucleotides with novel 2'-4' conformationaly restricted nucleoside analogues show improved potency without increased toxicity in animals.
PMID 19086780·J Med Chem·2009
7-preclinical
Potent inhibition of microRNA in vivo without degradation.
PMID 19015151·Nucleic Acids Res·2009
7-preclinical
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogs.
PMID 18776499·Nucleic Acids Symp Ser (Oxf)·2008
8-other
Structure-based design, synthesis, and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2" ether analogues of paromomycin.
PMID 17458946·J Med Chem·2007
7-preclinical
The positional influence of the helical geometry of the heteroduplex substrate on human RNase H1 catalysis.
PMID 17028157·Mol Pharmacol·2007
8-other
Competition for RISC binding predicts in vitro potency of siRNA.
PMID 16945958·Nucleic Acids Res·2006
8-other
RNA interference by 2',5'-linked nucleic acid duplexes in mammalian cells.
PMID 16616491·Bioorg Med Chem Lett·2006
7-preclinical
Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids.
PMID 16610796·J Med Chem·2006
7-preclinical
Trisaccharide mimetics of the aminoglycoside antibiotic neomycin.
PMID 16557321·Org Biomol Chem·2006
8-other
Improving RNA interference in mammalian cells by 4'-thio-modified small interfering RNA (siRNA): effect on siRNA activity and nuclease stability when used in combination with 2'-O-alkyl modifications.
PMID 16509579·J Med Chem·2006
7-preclinical
SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain.
PMID 16279767·J Med Chem·2005
8-other
Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.
PMID 16220989·J Med Chem·2005
7-preclinical
The synthesis and 16S A-site rRNA recognition of carbohydrate-free aminoglycosides.
PMID 16168642·Bioorg Med Chem Lett·2005
8-other
An efficient synthesis of gougerotin and related analogues using solid- and solution-phase methodology.
PMID 16048309·Org Lett·2005
8-other
Positional effect of chemical modifications on short interference RNA activity in mammalian cells.
PMID 15974578·J Med Chem·2005
7-preclinical
Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.
PMID 15715458·J Med Chem·2005
4-observational
Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site.
PMID 15593140·Angew Chem Int Ed Engl·2004
8-other

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Via practice · 6 locations total

Address
201 Highland St
Clinton, MA 01510

Locations (6)

Practice Location

201 Highland St, Clinton, MA
(508) 421-1400

Practice Location

510 N Main St, Leominster, MA
(508) 421-1400

Practice Location

60 Hospital Rd, Leominster, MA
(508) 421-1400

Practice Location

157 UNION ST, MARLBOROUGH, MA
(508) 421-1400

Practice Location

55 LAKE AVE N, WORCESTER, MA
(508) 421-1400

UMass Memorial Medical Center - Memorial Campus Emergency Room

119 BELMONT ST, WORCESTER, MA
2.8(508) 421-1400

Quick Facts

NPI
1821143694
Entity Type
Individual
Gender
Male
Medicare
Accepted
Specialties
1
Locations
6
Years in Practice
26
Publications
20

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