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JOSEPH COOLS, MD
MD
Child & Adolescent Psychiatry Physician
NPI: 1831128701Individual
Specialties, Licenses & Credentials
Child & Adolescent Psychiatry PhysicianPrimary
Psychiatry & Neurology — Child & Adolescent Psychiatry
Code: 2084P0804X
4301053783(MI)
Research & Publications (20)
The fusion proteins TEL-PDGFRbeta and FIP1L1-PDGFRalpha escape ubiquitination and degradation.
PMID 19644140·Haematologica·2009
7-preclinical
JAK1 mutation analysis in T-cell acute lymphoblastic leukemia cell lines.
PMID 19176360·Haematologica·2009
7-preclinical
FIP1L1-PDGFRalpha D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRalpha T674I eosinophilic leukemia with single agent sorafenib.
PMID 19212337·Leukemia·2009
5-case
Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia.
PMID 18923437·Leukemia·2009
8-other
The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia.
PMID 18299449·Blood·2008
8-other
Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies.
PMID 18401417·Leukemia·2008
7-preclinical
Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells.
PMID 18820131·Blood·2008
7-preclinical
Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.
PMID 18614052·Mol Cell·2008
7-preclinical
Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.
PMID 18794084·Clin Cancer Res·2008
7-preclinical
In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.
PMID 18322257·Haematologica·2008
8-other
Five years since the discovery of FIP1L1-PDGFRA: what we have learned about the fusion and other molecularly defined eosinophilias.
PMID 18843283·Leukemia·2008
6-review
Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion.
PMID 18166785·Haematologica·2008
5-case
Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation.
PMID 17979197·Hum Mutat·2008
8-other
Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCR-ABL1 fusion protein kinases.
PMID 18784740·Leukemia·2008
4-observational
Potentiation of antileukemic therapies by Smac mimetic, LBW242: effects on mutant FLT3-expressing cells.
PMID 17620426·Mol Cancer Ther·2007
7-preclinical
Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype.
PMID 17704776·Nat Genet·2007
8-other
Uniform sensitivity of FLT3 activation loop mutants to the tyrosine kinase inhibitor midostaurin.
PMID 17827387·Blood·2007
7-preclinical
Novel approaches to therapy of hypereosinophilic syndromes.
PMID 17868862·Immunol Allergy Clin North Am·2007
6-review
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 103 W US HIGHWAY 2
WAKEFIELD, MI 49968 - Phone
- (906) 229-6120
Quick Facts
- NPI
- 1831128701
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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