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JESUS PICHARDO, M.D.
M.D.
Pediatrics Physician
NPI: 1851468433Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
188066(NY)
Research & Publications (20)
Discovery of novel P3 sulfonamide-capped inhibitors of HCV NS3 protease. Inhibitors with improved cellular potencies.
PMID 19481946·Bioorg Med Chem·2009
7-preclinical
Design, synthesis, and evaluation of oxygen-containing macrocyclic peptidomimetics as inhibitors of HCV NS3 protease.
PMID 19154150·J Med Chem·2009
8-other
Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease.
PMID 19102654·J Med Chem·2009
8-other
Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034.
PMID 18421139·J Synchrotron Radiat·2008
8-other
Correlation between PAMPA permeability and cellular activities of hepatitis C virus protease inhibitors.
PMID 18164692·Biochem Pharmacol·2008
8-other
Potent and selective small molecule NS3 serine protease inhibitors of Hepatitis C virus with dichlorocyclopropylproline as P2 residue.
PMID 18032054·Bioorg Med Chem·2008
7-preclinical
Method for estimating skeletal spongiosa volume and active marrow mass in the adult male and adult female.
PMID 17942808·J Nucl Med·2007
8-other
A high-throughput assay for the adenylation reaction of bacterial DNA ligase.
PMID 17493575·Anal Biochem·2007
8-other
Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.
PMID 17444623·J Med Chem·2007
8-other
In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease.
PMID 17151003·J Antimicrob Chemother·2007
8-other
Linear regression model for predicting patient-specific total skeletal spongiosa volume for use in molecular radiotherapy dosimetry.
PMID 17079822·J Nucl Med·2006
8-other
Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection.
PMID 17004721·J Med Chem·2006
7-preclinical
Image segmentation of trabecular spongiosa by visual inspection of the gradient magnitude.
PMID 16953037·Phys Med Biol·2006
8-other
P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease.
PMID 16730985·Bioorg Med Chem Lett·2006
8-other
Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication.
PMID 16640336·J Med Chem·2006
7-preclinical
SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells.
PMID 16495264·Antimicrob Agents Chemother·2006
8-other
Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles.
PMID 16451065·J Med Chem·2006
8-other
Potent 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid-based macrocyclic inhibitors of hepatitis C virus NS3 protease.
PMID 16420042·J Med Chem·2006
8-other
Novel inhibitors of hepatitis C NS3-NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid.
PMID 16413182·Bioorg Med Chem Lett·2006
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1623 WEIRFIELD ST
RIDGEWOOD, NY 11385 - Phone
- (718) 456-4600
Quick Facts
- NPI
- 1851468433
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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