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EMMMANUEL BESSAY, MD
MD
Surgery Physician
NPI: 1881914315IndividualAccepts Medicare
Specialties, Licenses & Credentials
CMS Specialties
PrimaryGENERAL SURGERY
Education
NORTHWESTERN UNIVERSITY FEINBERG MEDICAL SCHOOL
Class of 2010
Research & Publications (9)
Phosphorylation increases affinity of the phosphodiesterase-5 catalytic site for tadalafil.
PMID 18199808·J Pharmacol Exp Ther·2008
7-preclinical
Phosphorylation of phosphodiesterase-5 is promoted by a conformational change induced by sildenafil, vardenafil, or tadalafil.
PMID 17127429·Front Biosci·2007
7-preclinical
Conversion of phosphodiesterase-5 (PDE5) catalytic site to higher affinity by PDE5 inhibitors.
PMID 17690252·J Pharmacol Exp Ther·2007
7-preclinical
A 46-amino acid segment in phosphodiesterase-5 GAF-B domain provides for high vardenafil potency over sildenafil and tadalafil and is involved in phosphodiesterase-5 dimerization.
PMID 16926278·Mol Pharmacol·2006
8-other
Correlation of seasonal acclimatization in metabolic enzyme activity with preferred body temperature in the Eastern red spotted newt (Notophthalmus viridescens viridescens).
PMID 16716618·Comp Biochem Physiol A Mol Integr Physiol·2006
7-preclinical
Structural and functional features in human PDE5A1 regulatory domain that provide for allosteric cGMP binding, dimerization, and regulation.
PMID 15677448·J Biol Chem·2005
8-other
Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation.
PMID 15213306·Mol Pharmacol·2004
8-other
Phosphorylation of isolated human phosphodiesterase-5 regulatory domain induces an apparent conformational change and increases cGMP binding affinity.
PMID 12359732·J Biol Chem·2002
8-other
A conserved serine juxtaposed to the pseudosubstrate site of type I cGMP-dependent protein kinase contributes strongly to autoinhibition and lower cGMP affinity.
PMID 12080049·J Biol Chem·2002
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
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Contact & Hours
- Address
- 927 BROADWAY ST, SUITE 121
QUINCY, IL 62301 - Phone
- (217) 224-6423
Quick Facts
- NPI
- 1881914315
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 16
- Publications
- 9
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