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GWYNNE HOLZ, M.D.
M.D.
Diagnostic Radiology Physician
NPI: 1912960857Individual
Specialties, Licenses & Credentials
Diagnostic Radiology PhysicianPrimary
Radiology — Diagnostic Radiology
Code: 2085R0202X
4301051288(MI)35059514H(OH)
Research & Publications (20)
Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells.
PMID 19593440·PLoS One·2009
7-preclinical
Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.
PMID 19244230·J Biol Chem·2009
7-preclinical
Cytosolic adenylate kinases regulate K-ATP channel activity in human beta-cells.
PMID 18243136·Biochem Biophys Res Commun·2008
7-preclinical
Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells.
PMID 18202100·J Physiol·2008
7-preclinical
Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach".
PMID 17989206·Am J Physiol Cell Physiol·2008
7-preclinical
Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.
PMID 17716863·Cell Signal·2008
6-review
A novel cyclic adenosine monophosphate responsive luciferase reporter incorporating a nonpalindromic cyclic adenosine monophosphate response element provides optimal performance for use in G protein coupled receptor drug discovery efforts.
PMID 17507637·J Biomol Screen·2007
7-preclinical
Simultaneous optical measurements of cytosolic Ca2+ and cAMP in single cells.
PMID 16985238·Sci STKE·2006
7-preclinical
cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.
PMID 16613879·J Physiol·2006
4-observational
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
PMID 15987680·J Biol Chem·2005
7-preclinical
A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells.
PMID 15860526·J Physiol·2005
7-preclinical
Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell.
PMID 14693691·Diabetes·2004
6-review
Glucagon-like peptide-1 synthetic analogs: new therapeutic agents for use in the treatment of diabetes mellitus.
PMID 14529486·Curr Med Chem·2003
6-review
Viral escape and T-cell immunity during ganciclovir treatment of cytomegalovirus infection: case report of a pancreatico-renal transplant recipient.
PMID 12640316·Transplantation·2003
5-case
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion.
PMID 12639990·J Clin Invest·2003
7-preclinical
Amplification of exocytosis by Ca2+-induced Ca2+ release in INS-1 pancreatic beta cells.
PMID 12509487·J Physiol·2003
4-observational
Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.
PMID 12496249·J Biol Chem·2003
8-other
Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells.
PMID 12410638·Biochem J·2003
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 2 locations total
- Address
- 1500 EAST MEDICAL CENTER DR, B1 FLOOR UNIVERSITY HOSPITAL RECP C
ANN ARBOR, MI 48109 - Phone
- (734) 936-4500
Quick Facts
- NPI
- 1912960857
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 2
- Publications
- 20
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