Back to Search
MARY WITTMAN, M.D.
M.D.
Obstetrics & Gynecology Physician
NPI: 1952481889Individual
Specialties, Licenses & Credentials
Obstetrics & Gynecology PhysicianPrimary
Obstetrics & Gynecology
Code: 207V00000X
MD00036040(WA)
Research & Publications (15)
Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase.
PMID 17187980·Bioorg Med Chem Lett·2007
7-preclinical
Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity.
PMID 16134929·J Med Chem·2005
7-preclinical
Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids.
PMID 11277526·Bioorg Med Chem Lett·2001
7-preclinical
Synthesis of metabolically blocked paclitaxel analogues.
PMID 11277525·Bioorg Med Chem Lett·2001
8-other
Discovery and evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an orally efficacious inhibitor of insulin-like growth factor-1 receptor kinase with broad spectrum in vivo antitumor activity.
PMID 18763755·J Med Chem·2008
7-preclinical
Balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-IR inhibitors.
PMID 18572407·Bioorg Med Chem Lett·2008
8-other
2-(1H-Imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924.
PMID 18258427·Bioorg Med Chem Lett·2008
7-preclinical
Thyroxine increases the rate but does not alter the pattern of innervation during embryonic chick corneal development.
PMID 18172086·Invest Ophthalmol Vis Sci·2008
7-preclinical
Imidazole moiety replacements in the 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one inhibitors of insulin-like growth factor receptor-1 (IGF-1R) to improve cytochrome P450 profile.
PMID 17398093·Bioorg Med Chem Lett·2007
7-preclinical
Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R).
PMID 17317169·Bioorg Med Chem Lett·2007
8-other
Challenges in the development of mGluR5 positive allosteric modulators: the discovery of CPPHA.
PMID 17210250·Bioorg Med Chem Lett·2007
7-preclinical
In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.
PMID 16397250·Cancer Res·2006
7-preclinical
Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor.
PMID 15867374·Cancer Res·2005
7-preclinical
Synthesis and antitumor activity of novel C-7 paclitaxel ethers: discovery of BMS-184476.
PMID 11741476·J Med Chem·2001
8-other
Insulin sensitivity and beta-cell secretion after liver transplantation in patients with acute liver failure.
PMID 11406252·Transplant Proc·2001
4-observational
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 12303 NE 130TH LN STE 450
KIRKLAND, WA 98034 - Phone
- (425) 899-5000
Quick Facts
- NPI
- 1952481889
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 15
Are you this provider?
Claim Your Profile