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NICHOLAS IRWIN, M.D.

M.D.

Emergency Medicine Physician

NPI: 1952694671IndividualAccepts Medicare

Specialties, Licenses & Credentials

Student in an Organized Health Care Education/Training Program

Student in an Organized Health Care Education/Training Program

Code: 390200000X

Emergency Medicine PhysicianPrimary

Emergency Medicine

Code: 207P00000X

47357(KY)

CMS Specialties

PrimaryEMERGENCY MEDICINE

Education

MEDICAL COLLEGE OF GEORGIA SCHOOL OF MEDICINE

Class of 2011

Research & Publications (20)

Active immunisation against gastric inhibitory polypeptide (GIP) improves blood glucose control in an animal model of obesity-diabetes.
PMID 18937625·Biol Chem·2009
7-preclinical
Prolonged GIP receptor activation using stable mini-PEGylated GIP improves glucose homeostasis and beta-cell function in age-related glucose intolerance.
PMID 19026698·Peptides·2009
7-preclinical
Antidiabetic effects of sub-chronic activation of the GIP receptor alone and in combination with background exendin-4 therapy in high fat fed mice.
PMID 19073224·Regul Pept·2009
7-preclinical
Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties.
PMID 19523458·Biochem Pharmacol·2009
7-preclinical
Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb.
PMID 19553458·J Neurosci·2009
7-preclinical
Metabolic effects of sustained activation of the GLP-1 receptor alone and in combination with background GIP receptor antagonism in high fat-fed mice.
PMID 19515180·Diabetes Obes Metab·2009
4-observational
Evidence for beneficial effects of compromised gastric inhibitory polypeptide action in obesity-related diabetes and possible therapeutic implications.
PMID 19533083·Diabetologia·2009
6-review
Variation in phenotype, parasite load and male competitive ability across a cryptic hybrid zone.
PMID 19479073·PLoS One·2009
7-preclinical
Effects of gastric inhibitory polypeptide (GIP) and related analogues on glucagon release at normo- and hyperglycaemia in Wistar rats and isolated islets.
PMID 18163884·Biol Chem·2008
7-preclinical
Antidiabetic effects of sub-chronic administration of the cannabinoid receptor (CB1) antagonist, AM251, in obese diabetic (ob/ob) mice.
PMID 18191122·Eur J Pharmacol·2008
7-preclinical
Daily administration of the GIP-R antagonist (Pro3)GIP in streptozotocin-induced diabetes suggests that insulin-dependent mechanisms are critical to anti-obesity-diabetes actions of (Pro3)GIP.
PMID 18333892·Diabetes Obes Metab·2008
4-observational
Comparison of independent and combined chronic metabolic effects of GIP and CB1 receptor blockade in high-fat fed mice.
PMID 18291559·Peptides·2008
4-observational
(Pro(3))GIP[mPEG]: novel, long-acting, mPEGylated antagonist of gastric inhibitory polypeptide for obesity-diabetes (diabesity) therapy.
PMID 18695644·Br J Pharmacol·2008
7-preclinical
C-terminal mini-PEGylation of glucose-dependent insulinotropic polypeptide exhibits metabolic stability and improved glucose homeostasis in dietary-induced diabetes.
PMID 18455149·Biochem Pharmacol·2008
7-preclinical
Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
PMID 18225986·Biol Chem·2008
7-preclinical
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1.
PMID 18184314·Eur J Neurosci·2008
7-preclinical
Long-term administration of antisense oligonucleotides into the paraspinal muscles of mdx mice reduces kyphosis.
PMID 18499783·J Appl Physiol (1985)·2008
7-preclinical
Comparison of the metabolic effects of GIP receptor antagonism and PYY(3-36) receptor activation in high fat fed mice.
PMID 17884253·Peptides·2007
4-observational
Effects of subchronic treatment with the long-acting glucose-dependent insulinotropic polypeptide receptor agonist, N-AcGIP, on glucose homeostasis in streptozotocin-induced diabetes.
PMID 17575548·Pancreas·2007
7-preclinical
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet.
PMID 17848629·Am J Physiol Endocrinol Metab·2007
7-preclinical

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
UNIVERSITY OF KENTUCKY, 800 ROSE ST.
LEXINGTON, KY 40536

Location

Practice Location

UNIVERSITY OF KENTUCKY, LEXINGTON, KY
(859) 323-5083

Quick Facts

NPI
1952694671
Entity Type
Individual
Gender
Male
Medicare
Accepted
Specialties
2
Locations
1
Years in Practice
15
Publications
20

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