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WICKHAM SIMONDS, MD
MD
Emergency Medicine Physician
NPI: 1972564235Individual
Specialties, Licenses & Credentials
Emergency Medicine PhysicianPrimary
Emergency Medicine
Code: 207P00000X
200000312(NC)
Research & Publications (20)
Assays of nuclear localization of R7/Gbeta5 complexes.
PMID 15488180·Methods Enzymol·2004
7-preclinical
Familial isolated hyperparathyroidism is rarely caused by germline mutation in HRPT2, the gene for the hyperparathyroidism-jaw tumor syndrome.
PMID 14715834·J Clin Endocrinol Metab·2004
8-other
G protein-regulated signaling dysfunction in human disease.
PMID 12929736·J Investig Med·2003
6-review
Familial isolated hyperparathyroidism: clinical and genetic characteristics of 36 kindreds.
PMID 11807402·Medicine (Baltimore)·2002
6-review
New dimensions in G protein signalling: G beta 5 and the RGS proteins.
PMID 10812978·Pharm Acta Helv·2000
6-review
The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene.
PMID 18987311·Proc Natl Acad Sci U S A·2008
4-observational
The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3.
PMID 18687124·Mol Cancer·2008
7-preclinical
R7-binding protein targets the G protein beta 5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain.
PMID 17880698·BMC Biochem·2007
7-preclinical
Ruling out a suspect: the role of beta-catenin mutation in benign parathyroid neoplasia.
PMID 17409343·J Clin Endocrinol Metab·2007
8-other
Nuclear localization of the parafibromin tumor suppressor protein implicated in the hyperparathyroidism-jaw tumor syndrome enhances its proapoptotic function.
PMID 17314275·Mol Cancer Res·2007
7-preclinical
The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations.
PMID 17299066·J Clin Endocrinol Metab·2007
8-other
Surveillance for early detection of aggressive parathyroid disease: carcinoma and atypical adenoma in familial isolated hyperparathyroidism associated with a germline HRPT2 mutation.
PMID 16995822·J Bone Miner Res·2006
5-case
Editorial: Imaging to detect early endocrine cancers.
PMID 16894022·J Clin Endocrinol Metab·2006
8-other
Adenylyl cyclase type-VIII activity is regulated by G(betagamma) subunits.
PMID 15925485·Cell Signal·2006
7-preclinical
Impaired cotranslational processing of the calcium-sensing receptor due to signal peptide missense mutations in familial hypocalciuric hypercalcemia.
PMID 15879434·Hum Mol Genet·2005
8-other
topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage.
PMID 15735665·Oncogene·2005
7-preclinical
Hereditary hormone excess: genes, molecular pathways, and syndromes.
PMID 15632315·Endocr Rev·2005
6-review
Parafibromin, product of the hyperparathyroidism-jaw tumor syndrome gene HRPT2, regulates cyclin D1/PRAD1 expression.
PMID 15580289·Oncogene·2005
7-preclinical
Multiple endocrine neoplasia type 1 variant with frequent prolactinoma and rare gastrinoma.
PMID 15292304·J Clin Endocrinol Metab·2004
4-observational
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 321 MULBERRY ST SW
LENOIR, NC 28645 - Phone
- (843) 237-3378
Quick Facts
- NPI
- 1972564235
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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