Overview
Clinical overview and emergency guidance are pending physician authorship. Graph-derived data (ontology codes, linked conditions, diagnostic biomarkers) is available below.
Associated Conditions
Conditions associated with this symptom based on HPO disease-phenotype annotations.
Globoid cell leukodystrophy, late-onset
Frequent (30-79%)
Niemann-Pick disease, type C
Occasional (5-29%)
Deficiency of guanidinoacetate methyltransferase
Occasional (5-29%)
Galactosylceramide lipidosis
Frequent (30-79%)
Phenylketonuria
Occasional (5-29%)
Early onset cerebellar ataxia with retained tendon reflexes
Occasional (5-29%)
Silver disease
Troyer syndrome
Always present (100%)
Galactocerebroside beta-galactosidase deficiency - early onset
Frequent (30-79%)
Chiari malformation type I
Congenital bilateral perisylvian syndrome
Occasional (5-29%)
Ataxia-telangiectasia-like disorder
PPMX - Mental retardation with psychosis, pyramidal signs, and macroorchidism
Frequent (30-79%)
Partington syndrome
Frequent (30-79%)
Fatty acid hydroxylase associated neurodegeneration
Always present (100%)
ARSACS - autosomal recessive spastic ataxia of Charlevoix-Saguenay
Frequent (30-79%)
Methyl-CpG (cytosine phosphate guanine) binding protein-2 duplication syndrome
Very frequent (80-99%)
Dilated cardiomyopathy with ataxia syndrome
Very rare (1-4%)
Spinocerebellar ataxia type 10
Occasional (5-29%)
Cerebellar ataxia with hypogonadism and choroidal dystrophy syndrome
Frequent (30-79%)
Cerebro-oculo-dento-auriculo-skeletal syndrome
Occasional (5-29%)
Juvenile amyotrophic lateral sclerosis
Very frequent (80-99%)
Congenital pontocerebellar hypoplasia type 6
Autosomal recessive spastic paraplegia type 39
Frequent (30-79%)
Leukoencephalopathy co-occurrent with bilateral anterior temporal lobe cysts
Very frequent (80-99%)
Quick Facts
- SNOMED CT
- 394679006
- UMLS CUI
- C1271100
- Fully Specified Name
- Lower limb spasticity (finding)
- Associated Conditions
- 25
- Diagnostic Tests
- 0
This information is for educational purposes only. If you are experiencing symptoms, please consult a healthcare provider for proper evaluation and diagnosis.