Substance / Medication

Cortisone

SNOMED 32498003 UMLS C0010137

Overview

Active Ingredient

cortisone

RxNorm CUI

2878

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Complement C3c

LOINC 4485-9

primary

Eosinophils

LOINC 711-2

primary

IgE

LOINC 19113-0

primary

Nuclear Ab

LOINC 8061-4

primary

Clinical Trials

4 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment

NCT03760835Phase 4Recruiting150 enrolled

Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) Study

NCT02261727Phase 4Completed1670 enrolled

Dual RElease Hydrocortisone Versus conventionAl Glucocorticoid replaceMent Therapy in Hypocortisolism (DREAM)

NCT02277587Phase 4Completed89 enrolled

Cortisone Injection vs Trigger Point Dry Needling Fin the Treatment of Greater Trochanter Pain Syndrome: A Pilot Study

NCT02639039Phase 4Completed50 enrolled

View all 4 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Physical Therapy Combined With Subacromial Cortisone Injection Is a First-Line Treatment Whereas Acromioplasty With Physical Therapy Is Best if Nonoperative Interventions Fail for the Management of Subacromial Impingement: A Systematic Review and Network Meta-Analysis.

Lavoie-Gagne Ophelie, Farah Ghassan, Lu Yining et al. · Arthroscopy · 2022

PMID: 35189304Meta-Analysis

A Double Blind Randomised Controlled Trial Comparing Glenohumeral Cortisone With and Without Hydrodilatation in Patients With Frozen Shoulder.

Konarski Alastair, Narayanasamy Kishen, Coghlan Jennifer et al. · ANZ J Surg · 2025

PMID: 40495621RCT

Effects of Obesity and Insulin on Tissue-Specific Recycling Between Cortisol and Cortisone in Men.

Anderson Anna J, Andrew Ruth, Homer Natalie Z M et al. · J Clin Endocrinol Metab · 2021

PMID: 33270115RCTFull text (PMC)

The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy.

Dineen Rosemary, Behan Lucy-Ann, Kelleher Grainne et al. · BMC Endocr Disord · 2020

PMID: 33036588RCTFull text (PMC)

[Management of Idiopathic Frozen Shoulder - Prospective Evaluation of Mobilisation under Anaesthesia and an Additional Subacromial Cortisone Injection].

Meyer C, Stein G, Kellinghaus J et al. · Z Orthop Unfall · 2015

PMID: 26367143RCT

Conversion of cortisone to cortisol and prostaglandin F2α production by the reproductive tract of cows at the late luteal stage in vivo.

Duong H T, Skarzynski D J, Piotrowska-Tomala K K et al. · Reprod Domest Anim · 2012

PMID: 22335619RCT

Feasibility of home-based sampling of salivary cortisol and cortisone in healthy adults.

Sørensen Sarah Overgaard, Pedersen Jesper, Rasmussen Martin G et al. · BMC Res Notes · 2021

PMID: 34727972TrialFull text (PMC)

The effect of subacromial injections of autologous conditioned plasma versus cortisone for the treatment of symptomatic partial rotator cuff tears.

von Wehren Lutz, Blanke Fabian, Todorov Atanas et al. · Knee Surg Sports Traumatol Arthrosc · 2016

PMID: 26017742Trial

Salivary Cortisone Reflects Cortisol Exposure Under Physiological Conditions and After Hydrocortisone.

Debono Miguel, Harrison Robert F, Whitaker Martin J et al. · J Clin Endocrinol Metab · 2016

PMID: 26812690Trial

Glucocorticoid Metabolism in Hypertensive Disorders of Pregnancy: Analysis of Plasma and Urinary Cortisol and Cortisone.

Kosicka Katarzyna, Siemiątkowska Anna, Krzyścin Mariola et al. · PLoS One · 2015

PMID: 26637176TrialFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Dermatology Physician

Dermatology

NUCC 207N00000X

Allergy & Immunology (Internal Medicine) Physician

Internal Medicine — Allergy & Immunology

NUCC 207RA0201X

Nephrology Physician

Internal Medicine — Nephrology

NUCC 207RN0300X

Rheumatology Physician

Internal Medicine — Rheumatology

NUCC 207RR0500X

Find a Provider

Health Goals

Goals connected through associated conditions

Manage Autoimmune Risk Promote Skin Health

Quick Facts

Type: Substance / Medication
Fully Specified Name: Cortisone (substance)
SNOMED CT: 32498003
UMLS CUI: C0010137
RxNorm CUI: 2878

Clinical Data

This intervention maps to 30 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.