Substance / Medication

Guanidine

Overview

Active Ingredient
guanidine
RxNorm CUI
50675

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Iodine-131-meta-iodobenzylguanidine therapy for patients with newly diagnosed high-risk neuroblastoma.
Kraal Kathelijne Cjm, van Dalen Elvira C, Tytgat Godelieve Am et al. · Cochrane Database Syst Rev · 2017
PMID: 28429876Meta-AnalysisFull text (PMC)
A systematic review of 131I-meta iodobenzylguanidine molecular radiotherapy for neuroblastoma.
Wilson Jayne S, Gains Jennifer E, Moroz Veronica et al. · Eur J Cancer · 2014
PMID: 24333097Meta-Analysis
Is there a role for radioguided surgery with iodine-labeled metaiodobenzylguanidine in resection of neuroendocrine tumors?
van Hulsteijn Leonie T, Corssmit Eleonora P M, van der Hiel Bernies et al. · Clin Nucl Med · 2012
PMID: 22996242Meta-Analysis
123I-meta-iodobenzylguanidine scintigraphy for the detection of neuroblastoma and pheochromocytoma: results of a meta-analysis.
Jacobson Arnold F, Deng Hsiaowei, Lombard John et al. · J Clin Endocrinol Metab · 2010
PMID: 20392867Meta-Analysis
Prognostic value of myocardial 123I-metaiodobenzylguanidine (MIBG) parameters in patients with heart failure: a systematic review.
Verberne Hein J, Brewster Lizzy M, Somsen G Aernout et al. · Eur Heart J · 2008
PMID: 18349024Meta-Analysis
Polyhexamethylene guanidine phosphate irrigation as an adjunctive to scaling and root planing in the treatment of chronic periodontitis.
Vitt Anton, Gustafsson Anders, Ramberg Per et al. · Acta Odontol Scand · 2019
PMID: 30632852RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Guanidine (substance)
SNOMED CT
109108004
UMLS CUI
C0120446
RxNorm CUI
50675

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.