Substance / Medication

Guanidine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
A comparative study on the aggregating effects of guanidine thiocyanate, guanidine hydrochloride and urea on lysozyme aggregation.
Emadi Saeed, Behzadi Maliheh · Biochem Biophys Res Commun · 2014
PMID: 25003319Observational
[Comparative in vitro antibacterial activity of polyhexamethylene guanidine hydrochloride and polyhexamethylene guanidine succinate].
Kha Kam An', Grammatikova N É, Vasilinko I A et al. · Antibiot Khimioter · 2013
PMID: 24640138Observational
Interactions of biocidal guanidine hydrochloride polymer analogs with model membranes: a comparative biophysical study.
Zhou Zhongxin, Zheng Anna, Zhong Jianjiang · Acta Biochim Biophys Sin (Shanghai) · 2011
PMID: 21807631Observational
Stability profiles of nepenthesin in urea and guanidine hydrochloride: comparison with porcine pepsin A.
Kubota Keiko, Metoki Yuya, Athauda Senarath B P et al. · Biosci Biotechnol Biochem · 2010
PMID: 21071863Observational
Cell division is essential for elimination of the yeast [PSI+] prion by guanidine hydrochloride.
Byrne Lee J, Cox Brian S, Cole Diana J et al. · Proc Natl Acad Sci U S A · 2007
PMID: 17606924ObservationalFull text (PMC)
Comparison of guanidine hydrochloride (GdnHCl) and urea denaturation on inactivation and unfolding of human placental cystatin (HPC).
Rashid Fouzia, Sharma Sandeep, Bano Bilqees · Protein J · 2005
PMID: 16284726Observational
Small amounts of urea and guanidine hydrochloride can be detected by a far-UV spectrophotometric method in dialysed protein solutions.
Fuertes Miguel Angel, Pérez José Manuel, Alonso Carlos · J Biochem Biophys Methods · 2004
PMID: 15165752Observational
pH-dependent stability of sperm whale myoglobin in water-guanidine hydrochloride solutions.
Shosheva A, Miteva M, Christova P et al. · Eur Biophys J · 2003
PMID: 12582821Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Guanidine hydrochloride (substance)
SNOMED CT
412195000
UMLS CUI
C0120447

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.