Substance / Medication

Prednisolone

Overview

Active Ingredient
prednisolone
RxNorm CUI
8638

Indications

Prednisolone Oral Solution USP is indicated in the following conditions: 1. Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice: synthetic analogs may be used in conjunction with mineralocorticoids where applicable: in infancy mineralocorticoid supplementation is of particular importance). Congenital adrenal hyperplasia Nonsuppurative thyroiditis Hypercalcemia associated with cancer 2. Rheumatic Disorders As adjunctive therapy fo

Labeler: A-S Medication SolutionsUpdated: 2026-01-23T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Systemic fungal infections.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

102 trials linked to this intervention

102
Total Trials
36
Recruiting
19
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Adrenocorticotropic Hormone versus Prednisolone for Infantile Epileptic Spasms Syndrome: A Systematic Review and Economic Evaluation.
Gao Ruonan, Cheng Xiao, Huang Liang et al. · Neuropediatrics · 2025
PMID: 39900086Meta-Analysis
Highlighting inaccurate data supporting prednisolone administration in recurrent pregnancy loss: Comments on frequently cited meta-analysis.
Béquet Y L B N, van der Hoorn M L P, Lashley E E L O · Am J Reprod Immunol · 2024
PMID: 38414234Meta-Analysis
Identifying the Lowest Effective Initial Dose of Prednisolone for the Treatment of Subacute Granulomatous Thyroiditis: A Systematic Review and Meta-Analysis.
Soltani Akbar, Nourani Fatemeh, Roudsari Sahar Behnam et al. · Curr Rev Clin Exp Pharmacol · 2022
PMID: 34636318Meta-Analysis
Effectiveness of prednisolone in complex regional pain syndrome treatment: A systematic narrative review.
Kwak Sang Gyu, Choo Yoo Jin, Chang Min Cheol · Pain Pract · 2022
PMID: 34779145Meta-Analysis
Comparison of Clinical Outcome between Dexamethasone and Methyl Prednisolone in Treatment of Moderate to Severe COVID-19: A Systematic Review and Meta-Analysis.
Mohanty Rashmi Ranjan, Das Smita, Padhy Biswa Mohan et al. · J Assoc Physicians India · 2022
PMID: 35062806Meta-Analysis
Effectiveness of pulse dose methyl prednisolone in management of COVID 19: A systematic review and meta-analysis of observational studies.
Mohanty Rashmi Ranjan, Biswa Mohan Padhy, Meher Bikash Ranjan · J Pharm Pharm Sci · 2022
PMID: 35364003Meta-Analysis
Dexamethasone Versus Prednisone or Prednisolone for Acute Pediatric Asthma Exacerbations in the Emergency Department: A Meta-Analysis.
Cai Kai-Jin, Su Shi-Qing, Wang Yao-Guo et al. · Pediatr Emerg Care · 2021
PMID: 32149991Meta-Analysis
Meta-analyses of deflazacort versus prednisone/prednisolone in patients with nonsense mutation Duchenne muscular dystrophy.
Shieh Perry B, Elfring Gary, Trifillis Panayiota et al. · J Comp Eff Res · 2021
PMID: 34693725Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Prednisolone (substance)
SNOMED CT
116601002
UMLS CUI
C0032950
RxNorm CUI
8638
Labeler
A-S Medication Solutions

Clinical Data

This intervention maps to 34 entities in the Ltrl knowledge graph.

20
Conditions
7
Biomarkers
5
Specialists
0
Symptoms
102
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.