Search Nick Jikomes's Archive
Every thread, article and publication Nick Jikomes has here, searchable by title or by the words inside.
Showing 30 of 35 items in this Archive
- ArticleAug 19, 2026How To Support Mind & Matter
A short post explaining how you can help M&M grow and sustain itself.
- ArticleAug 19, 2026Eat Less, Move More?
The energy balance model cannot explain the dramatic rise in obesity, especially in a world contaminated with unavoidable obesogens.
- ArticleAug 19, 2026mRNA Shots & Acquired Immune Deficiency
A new study shows that mRNA shots can result in concerning immune system abnormalities, even in people with no prior SARS-CoV-2 infection.
- ArticleAug 19, 2026Dietary Fat, Sunscreen & Skin Photosensitivity: Can Seed Oils Promote Sunburn?
The body's sensitivity to the world depends on what you feed it.
- ArticleAug 19, 2026Trusting the Science: Do Diet Researchers Know What's in the Diets They Research?
Diet research is filled with poorly controlled studies, misprinted diet information, and irreproducible methods.
- ArticleAug 19, 2026Seed Oils & Body Fat: When did modern obesity rates begin rising?
Obesity started rising sooner than many realize. Seed oils correlate with obesity rates better than saturated fat or carbs.
- ArticleAug 19, 2026Seed Oils & Body Fat: Endocannabinoid Regulation of Energy Storage & Acquisition
The endocannabinoid system coordinates metabolic changes across the brain and body to favor energy storage. Dietary ω-6 PUFAs boost endogenous cannabinoids.
- ThreadJul 8, 2026GHK-Cu Peptide Effects on Iron and Lipid Peroxidation
Discussion of GHK-Cu's mechanisms involving ferritin iron release and lipid peroxidation toxins
- ThreadJun 5, 2026Omega-6 to Omega-3 Conversion in Fat-1 Genetically Engineered Mice
Thread examining fat-1 gene effects on PUFA balance and metabolic outcomes in mice
- ThreadMay 29, 2026Thread on Omega-3 and Omega-6 Fatty Acids in Human Milk
Data on regional variations in breast milk PUFA content and maternal supplementation effects
- ThreadMay 25, 2026Thread discussing motivations behind anti-aging and longevity practice
X user examines whether appearance or health drives longevity-focused behaviors
- ThreadMay 22, 2026Thread on Meta-Analysis Methods in Nutrition Research
A critical examination of dietary fat studies and food intake measurement methodology
- ThreadMay 22, 2026Thread on Genetic Variation in PUFA Processing and Seed Oils
Discussion of how genetic types affect dietary polyunsaturated fatty acid metabolism across ancestries
- ThreadMay 12, 2026Thread on Linoleic Acid and EPA Tissue Levels by @trikomes
Discussion of an RCT showing dietary linoleic acid effects on omega-3 and omega-6 ratios
- ThreadApr 29, 2026Omega-6 and Omega-3 Fats: Inflammation and Tissue Density
A thread exploring how ω-6 and ω-3 fatty acid intake affects tissue levels and inflammation regulation.
- ThreadApr 28, 2026Linoleic Acid Intake and Omega-3 EPA Conversion: RCT Discussion
Thread examining an RCT on how linoleic acid levels may affect endogenous EPA conversion
- ThreadApr 10, 2026Lyon Diet Heart Study: Mediterranean Diet Trial Results
X thread examining the Lyon Diet Heart Study's fatty acid composition and cardiac event outcomes
- ThreadApr 6, 2026Thread on Choline Deficiency, Liver Health, and Dietary Sources
A discussion of choline's role in lipid metabolism and its relationship to fatty liver disease.
- ThreadMar 26, 2026Thread analyzing omega-6 PUFA research and inflammatory markers
Examining claims about seed oils, CRP levels, and interpretation of an RCT comparing canola and sunflower oil
- ThreadMar 19, 2026Thread on Oxylipins, PUFAs, and Dietary Fats in Mice
X thread discussing research on polyunsaturated fatty acids and weight gain in mouse studies
- ThreadMar 3, 2026Neuroscientist explains appetite-specific circuits and reward pathways
Discussion of hypothalamic circuits, AgRP neurons, and how weight loss drugs interact with reward signaling
- ThreadFeb 13, 2026Diet, Drugs, and Sun Sensitivity: A Thread on Oxidative Stress
Discussion of how food and medications may affect skin's response to sunlight
- ThreadFeb 9, 2026Thread discussing seed oil consumption in Asian countries vs US
X thread analyzing claims about seed oil intake, omega-6 to omega-3 ratios, and chronic disease trends
- ThreadFeb 3, 2026Personal Glucose Monitor Experiment and Food Response Data
X thread documenting individual blood sugar responses to various foods over several days
- ThreadDec 31, 2025Exercise Performance, Carbohydrate Intake, and Metabolic Health
Discussion on high-carb vs. ketogenic diets and athletic performance with @AKoutnik
- ThreadDec 21, 2025Thread discussing PUFA inflammation studies in human tissue
X thread examining tissue-specific lipid mediator measurements versus serum inflammatory markers
- ThreadNov 14, 2025GLP-1 Drugs and Arachidonic Acid: A Thread on Dietary Fats
Discussion exploring the relationship between GLP-1 drugs, arachidonic acid, and dietary fat sources
- ThreadNov 11, 2025Vitamin D3 Supplements vs. Sunlight: Different Immune Effects
X thread discussing a study comparing immune pathway responses to oral vitamin D3 versus UVB exposure.
- ThreadNov 5, 2025Genetically Modified Mice and Omega-6 to Omega-3 Conversion Study
Research thread on engineered mice converting ω-6 to ω-3 PUFAs and high-fat diet responses
- ThreadOct 26, 2025Thread on Seed Oils, Omega-6 PUFAs, and Obesity Correlations
A discussion of population trends, metabolic mechanisms, and dietary fat research